...e-entry)thatcouldarisefromchangesingapjunctionalproteins,especiallyconnexin43(Cx43).WestudiedCx43expressionandphosphorylationstateintheleftventricle(LV)fromanarrhythmogenicrabbitmodelofnonischemicHFandfrompatientswithHFattributabletoidiopathicdilatedcardiomyopathy.Wealsoinvestigatedtheroleofproteinp...
参考资料医源资料库；在线期刊；循环研究杂志；2005年第95卷第1期【摘要】Thepredominanttesticulargapjunctionalproteinconnexin43(cx43)islocatedbetweenneighboringSertolicells(SCs)andbetweenSCsandgermcells.Itisassumedtobeinvolvedintesticulardevelopment,celldifferentiation,initiation,andmaintenanceofspermatogenesiswithalterationsofitsexpressionbeingcorrelatedwith...
参考资料医源资料库；在线期刊；美国病理学杂志；2007年第169卷第7期...schemicpreconditioningislostincardiomyocytesandheartsofheterozygousconnexin43deficient(Cx43+/eC)mice.Becauseconnexin43(Cx43)islocalizedincardiomyocytemitochondriaandmitochondrialCx43contentisincreasedwithischemicpreconditioning,wenowtriedtoidentifyafunctionaldefectatthelevelofthemitochondriainCx43+/...
参考资料医源资料库；在线期刊；循环研究杂志；2005年第95卷第9期...ve-Vasculardiseasealtersandreducesconnexinexpressionandareductioninconnexin43(Cx43)expressiondiminishestheextentofatherosclerosisobservedinahigh-cholesteroldietmurinemodel.Wehypothesizedthatconnexinsmightplayaroleinthesmoothmusclecellresponsetovascularinjury.MethodsandResults-Wethereforestudiedaline...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第5期...ofcellstoPDGFcausesrapidandtransientdisruptionofGJICwithoutalteringconnexin43(Cx43)proteinlevel.Inthisstudy,weinvestigatedlong-termeffectsofPDGF-BBonCx43expressioninmesangialcells(MCs).ExposureofMCstoPDGF-BBaffectedneithertheCx43proteinlevelnorGJIC.However,inthepresenceofcAMP-elevatingagents,PDGF-BB...
参考资料医源资料库；在线期刊；美国生理学杂志；2006年第289卷第5期...bstractSpecificmutationsinGJA1,thegeneencodingthegapjunctionproteinconnexin43(Cx43),causeanautosomaldominantdisordercalledoculodentodigitaldysplasia(ODDD).Here,wecharacterizetheeffectsof8ofthesemutationsonCx43function.Immunochemicalstudieshaveshownthatmostofthemutantproteinsformedgapjunctionplaquesa...
参考资料医源资料库；在线期刊；循环研究杂志；2005年第95卷第5期...omethods(micromanipulationandplatingassay)andtodetermineifthesecretionofthe43-kDaglycoprotein(gp43)isdependentontheclonalculture.Theresultsshowthatthesecretionofgp43isnotdependentonclonalcultures.Clonesthatoriginallyweresecretorsofthismolecule,aftersubculturing,lostthischaracteristic;ontheotherhand,...
参考资料医源资料库；在线期刊；微生物临床杂志；2005年第43卷第1期...dbytheproteinkinaseA(PKA)eCdependentsignal,andthattheaccumulationofconnexin43(Cx43),themostabundantCxinmyocytes,isenhancedbyanexchangeproteindirectlyactivatedbycAMP(Epac)(Rap1activator)eCdependentsignal.ThegatingfunctionofGJswasanalyzedbymicroinjecteddyetransfermethod.TheaccumulationofCx43wasanalyze...
参考资料医源资料库；在线期刊；循环研究杂志；2005年第95卷第9期...axial,pulsatilestretch.Changesinexpressionofthecardiacgapjunctionprotein,Cx43,weremeasuredbyconfocalmicroscopyandimmunoblotting.CellsgrownonfibronectinordenaturedcollagenexhibitedsignificantlygreaterCx43expressionthancellsgrownonnativecollagen.Stretchinduceda2-foldincreaseinCx43expressionincellsgrow...
参考资料医源资料库；在线期刊；循环研究杂志；2005年第95卷第3期....80元/公斤内蒙古内蒙古扎鲁特旗鲁北镇医药公司06-09-1210:43麻黄3.50元/公斤内蒙古内蒙古扎鲁特旗鲁北镇医药公司06-09-1210:43车前子2.10元/公斤内蒙古内蒙古扎鲁特旗鲁北镇医药公司06-09-1210:43蒲公英1.80元/公斤内蒙古内蒙古扎鲁特...
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