找到124215条结果，用时0.858s
  • AnthocyaninPreventsCD40-ActivatedProinflammatorySignalinginEndothelialCellsbyRegulatingCholesterolDistribution

    ...receptor-associatedfactors(TRAFs)translocationtolipidraftsisakeyelementinCD40-inducedsignaling.ThepurposeofthisstudywastoinvestigatetheinfluenceofanthocyaninonCD40-mediatedproinflammatoryeventsinhumanendothelialcellsandtheunderlyingpossiblemolecularmechanism.MethodsandResults-Treatmentofendothelialc...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第3期
  • Cholesterol-Dependentand-IndependentCD40InternalizationandSignalingActivationinCardiovascularEndothelialCells

    【摘要】Objective—ItremainselusivehowCD40endocytosisorclusteringonthecellsurfaceisinducedbydifferentformsofCD40agonist.ThisstudyaimstoinvestigatewhetherlipidraftsdifferentiallyregulateCD40trafficandsignalinginproinflammatoryactivationofcardiovascularendothelialcells(ECs).MethodsandResults&...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第9期
  • BiologicallyActiveCD40LigandIsElevatedinSickleCellAnemia

    【摘要】Objective-Afteractivation,plateletsexposeCD40ligand(CD40L)ontheirsurface,thensubsequentlyreleasetheinflammatorymediatorasasolublefragment(sCD40L).Becausesicklecellanemia(SCA)isnotedforbothplateletactivationandchronicinflammation,weaskedwhetherplatelet-releasedCD40Lpotentiallyplaysarolein...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期
  • SolubleCD40LLevelsAreRegulatedbythe-3459AGPolymorphismandPredictMyocardialInfarctionandtheEfficacyofAntithromboticTreatmentinNon-STEleva

    【摘要】Objectives-CurrentevidencesuggeststheCD40-CD40Lpathwayasakeyprocessinthedevelopment,progression,andoutcomeofacutecoronarysyndrome(ACS).Theaimwastoinvestigatetheprognosticimportanceofsoluble(s)CD40Llevels,singlenucleotidepolymorphisms(SNP)intheCD40LGgene,andtherelationbetweensCD40LandSNPs...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期
  • AssociationsBetweenSolubleCD40Ligand,AtherosclerosisRiskFactors,andSubclinicalAtherosclerosis

    ...urposeofthisstudywastoevaluatetheassociationsbetweenplasmalevelsofsolubleCD40ligand(sCD40L),atherosclerosisriskfactors,andevidenceofsubclinicalatherosclerosis.MethodsandResults—PlasmalevelsofsCD40Lweremeasuredin2811subjectsfromtheDallasHeartStudy,amultiethnicpopulation-basedcross-sectionalstudy.El...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第10期
  • CD40L-PositivePlateletsInduceCD40LExpressionDeNovoinEndothelialCells:AddingaLooptoMicrovascularInflammation

    ...ticlebyWagneretal,inwhichtheauthorselegantlyshowedthatmembraneboundCD154(CD40ligand)expressedbyT-cellscaneffectivelytriggerCD40Lexpressionbyendothelialcells.Moreimportantly,theauthorsdemonstratedafunctionalactivityofendothelium-associatedCD40L,thusrevealinganovelcostimulatoryactivityinmonocyte–end...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第9期
  • ReplacementofConnexin40byConnexin45intheMouseImpactonCardiacElectricalConduction

    ...nofcardiacimpulse,areintercellularstructurescomposedofconnexins(Cx).Cx43,Cx40,andCx45aresynthesizedinthecardiomyocytes,andeachofthemhasauniquecardiacexpressionpattern.Cx40knock-inCx45miceweregeneratedtoexploretheabilityofCx45toreplaceCx40,andtoassessthefunctionalequivalenceofthesetwoCxsthatarebothex...

    参考资料医源资料库；在线期刊；循环研究杂志；2004年第94卷第1期
  • TRAF-1,-2,-3,-5,and-6AreInducedinAtheroscleroticPlaquesandDifferentiallyMediateProinflammatoryFunctionsofCD40LinEndothelialCells

    【摘要】Objective-SeverallinesofevidenceimplicateCD40ligand(CD40L,CD154)asamediatorandmarkerofatherosclerosis.Thisstudyinvestigatedtheinvolvementoftumornecrosisfactorreceptor-associatedfactors(TRAFs)inCD40signalinginendothelialcells(ECs)andtheirexpressioninatheromataandcellsinvolvedinatherogenes...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第5期
  • InterruptionoftheTnfrsf4/Tnfsf4(OX40/OX40L)PathwayAttenuatesAtherogenesisinLow-DensityLipoproteinReceptor-DeficientMice

    ...mmatorydiseaseandTcellactivationisanimportantfactorinthisprocess.Tnfrsf4(OX40)andTnfsf4(OX40ligand)aremembersofthetumornecrosisfactor(TNF)andTNFreceptorfamilyandOX40/OX40Lmediatedsignalingisimportantinco-activationofTcellsandfacilitatesB-Tcellinteraction.InthisstudyweassessedtheroleoftheOX40/OX40Lpa...

    参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第1期
  • 十、SP40/40

    十、SP40/40　　自1982年起，生物科学技术文献中先后提出一批术语。后经鉴定它们都是蛋白质，且结构类同、功能相近，与补体的末端成分相关。这些成分有不同的名称：如Clusterin、SGP-2、SP40/40、TRRM-2、T64、GP111、SP80、CLI、apo-J...

    参考资料医源资料库；医源图书馆；教材类；细胞和分子免疫学

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