...tyDiversityofneuronalnicotinicacetylcholinereceptorbindingwasmeasuredusing[3H]epibatidineafterdeletionof7,2,or4subunits.[3H]Epibatidinebindingisdistinctlybiphasic.Densitiesofhigher(Kd0.02nM)andlower(Kd5nM)affinitysitesinwholebrainsofwild-typemiceareverysimilar.Relativesensitivitytoinhibitionbycytisi...
参考资料医源资料库；在线期刊；分子药理学杂志；2006年第68卷第9期...withnicotinicreceptorsubunit-deficientmicetocharacterizenAChRsthatmodulate[3H]nore-pinephrinereleasefromsynaptosomes.TheresultsindicatethatatleasttwopopulationsofnAChRscontributetothisrelease:anovel6(4)234subtypeandan6(4)23subtype.Thesearedistinctfromsubtypesthatmodulatesynaptosomalnorepinephrinerel...
参考资料医源资料库；在线期刊；分子药理学杂志；2006年第68卷第9期抗胃癌鼠单抗3H11Fab段载体的构建、表达及抗体活性检测中华微生物学和免疫学杂志1999年第2期第19卷基因工程抗体作者：李竞 王琰 王卓智 董志伟单位：李竞（北京医科大学博士生） 王琰（100037北京解放军海军总医院）；...
参考资料合作平台；医学论文；临床医学与专科论文；检验医学...mAChRs,dependingonthechemicalnatureoftheorthostericradioligandthatwasused[[3H]N-methylscopolamine([3H]NMS)versus[3H]quinuclidinylbenzilate([3H]QNB)].Thelargestwindowforobservinganeffect(negativecooperativity)wasnotedforthecombinationofWIN62,577and[3H]QNBattheM4mAChR.Experimentsinvolvingthecombinatio...
参考资料医源资料库；在线期刊；分子药理学杂志；2006年第68卷第8期...reused.MutantshadincreasedHDLcholesterol.HDLwaslabeledwith125I(protein)and[3H](CE).AfterHDLinjection,bloodsamplesweredrawnandfinallythemicewereeuthanized.InWT,theplasmadecayofHDL-associated[3H]isfastercomparedwith125Iandthisrepresentswhole-bodyselectiveCEuptake.InSR-BIKO,thedecayofbothtracersissimil...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第1期...ritiatedderivativeof(2S,3S)-3-{3-[4-ethylbenzoylamino]benzyloxy}aspartate([3H]ETB-TBOA).[3H]ETB-TBOAshowedsignificanthigh-affinityspecificbindingtoEAAT-transfectedCOS-1cellmembraneswitheachEAATsubtype.TheHillcoefficientfortheNa+-dependenceof[3H]ETB-TBOAbindingrevealedasingleclassofnoncooperativebind...
参考资料医源资料库；在线期刊；分子药理学杂志；2007年第69卷第1期...dcGVHinB6micecarryingtwodifferentHchainIgsite-directedtransgenes(sd-tg),the3H9knock-in(KI;reference6),andthe3H9/56R.KI(18),whichpossessanincreasedfrequencyofanti-DNABcells.Previousstudieshaveshownthatthe3H9HchainplaysakeyroleindeterminingDNAspecificity.WhenpairedwithmostbutnotallLchains,itgivesriset...
参考资料医源资料库；在线期刊；美国病理学杂志；2003年第162卷第1期...dcGVHinB6micecarryingtwodifferentHchainIgsite-directedtransgenes(sd-tg),the3H9knock-in(KI;reference6),andthe3H9/56R.KI(18),whichpossessanincreasedfrequencyofanti-DNABcells.Previousstudieshaveshownthatthe3H9HchainplaysakeyroleindeterminingDNAspecificity.WhenpairedwithmostbutnotallLchains,itgivesriset...
参考资料医源资料库；在线期刊；实验医学杂志；2003年第197卷第1期...omparedvascularremodeling(inducedby2weeksoflowflow)in2strainswithsmallIMT(C3H/HeJandC3HeB/FeJ)versus2strainswithlargeIMT(FVB/NJandSJL/J).QuantitativeimmunohistochemistryshowedadramaticincreaseininflammatorycellsperintimaareainSJLcomparedwithotherstrains.MicroarrayprofilingofinflammatorygenemRNAsfrom...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第2期...)6：5.30(1H，d，J=5．2Hz，H．6)，3．50(1H，m，H•3)，0．98(3H，s，H-19)，0．9l(3H，d，J=6．5Hz，H．21)，0．83(3H，d，J=1．8Hz，H一29)，O．81(3H，d，J=4．0Hz，H-27)，0．80(3H，s，H-26)，0．67(3H，s，H-18)；13CNMR(CDCl3，500MHz)6：19．8q，19．4q，19...
参考资料药品天地；专业药学；中药大全；中药材生产技术及质量管理；药用植物栽培管理