...yofNewYork,NewYork,NY;1:3000),largeconductancevoltage-andBKchannel-subunit(APC021,1:100;Alomone,Jerusalem,Israel)andtyrosinekinaseBneurotrophinreceptor(1:100;SantaCruzBiotechnology,SantaCruz,CA).Thefollowingfluorescein-conjugatedsecondaryantibodiesfromMolecularProbeswereusedata1:500dilution:highlycr...
参考资料医源资料库；在线期刊；美国病理学杂志；2007年第169卷第8期...edFabgoatanti–mouseIgG(JacksonImmunoResearchLaboratories)andstreptavidin-APC(BDBiosciences).Thestainedcellsweresuspendedinphenolred-freeHBSScontainingCa2+andMg2+(GIBCOBRL)andwereincubatedwithrotationfor45minatroomtemperaturein10μMFura-red,5μMFluo-3(preparedas1mMstocksin100%DMSO;MolecularProbes),...
参考资料医源资料库；在线期刊；实验医学杂志；2005年第201卷第1期...gensintheliverandintestine.WeshowMTPRNAandproteininantigen-presentingcells(APCs)byreversetranscription–polymerasechainreactionandbyimmunoblottingofmouselivermononuclearcellsandmouseandhumanBcelllines.FunctionalMTP,demonstratedbyspecifictriglyceridetransferactivity,ispresentinbothmousesplenocytesan...
参考资料医源资料库；在线期刊；实验医学杂志；2005年第202卷第4期...tedwitheffectorCD4+CD25-TcellsfromthelatteranimalsinthepresenceofirradiatedAPC.Figureshows1representativeexperimentof4.Thymidineuptakewasusedforassessmentofeffectorcellproliferativeindices.D,ThecomparativeeffectofTregsfromApoE-KOandC57BL/6miceexpressedaspercentinhibitionofresponderTcells.E,Spleencel...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第4期...nJD(1997)R-flurbiprofenchemopreventionandtreatmentofintestinaladenomasintheAPC(Min)/+mousemodel:implicationsforprophylaxisandtreatmentofcoloncancer.CancerRes57:4316eC4324.WechterWJ,LeipoldDD,MurrayEDJr,QuiggleD,McCrackenJD,BarriosRS,andGreenbergNM(2000)E-7869(R-flurbiprofen)inhibitsprogressionofpros...
参考资料医源资料库；在线期刊；分子药理学杂志；2005年第67卷第2期...eitsowngenerationthroughactivationoftheproteinCpathway.11ActivatedproteinC(APC)inactivatescofactorsVaandVIIIa,therebybluntingthrombingeneration.Thrombinalsoparticipatesdirectlyinitsfinalinhibitionandclearancefromthecirculationbyspecificallyrecognizingtheserpinsantithrombin(AT)andheparincofactorII(HC...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第8期...)细胞因子治疗(如干扰素);(2)治疗性疫苗;(3)抗原提呈细胞(APCs)的非特异性激活剂。目前采用预防接种HBsAg疫苗或免疫复合物，APCs的非特异性激活剂，具有潜在抗HBV作用。但处于临床前期阶段。细胞因子治疗，如干扰素具有良好的...
参考资料医源资料库；在线期刊；中华中西医杂志；2011年第12卷第2期...ppeartoinvolveoverlappingsubsetsoffactorsincludingadenomatouspolyposiscoli(APC),centrosomin,andadherensjunction–relatedcadherinsandcatenins(42-44).Whetherstemcellsnormallyundergoasymmetricdivisioninmammalsastheydoininvertebratesisyettobedetermined.Theimpactofthenichesizeoncontrollingthenumberofste...
参考资料医源资料库；在线期刊；临床研究杂志；2006年第116卷第5期...周围尚不肯定机制、：程序性细胞死亡（PCD）克降不应答APC缺乏协同刺激因子多价抗原与不成熟B细胞结合抗原性质可溶性蛋白质静脉或口服无佐剂参与大剂量多糖类抗原多聚蛋白质抗原（重复表位）无TH参与耐受期限期限长期限...
词条...redbloodcellswerelysed,andmononuclearcellsweresurfacestainedwithanti–CD4-APCandintracellularstainedwithanti–IL-17oranti–IFN-asdescribedbefore.Bloodwascollectedandlysed(RBClysisbuffer;Sigma-Aldrich),andmononuclearcellsfrombrainsandspinalcordtissuewerepreparedasdescribedpreviously(1)andsurfacest...
参考资料医源资料库；在线期刊；实验医学杂志；2005年第201卷第2期