...reaimedatperiodicallyblockingsignaltransductioninTcellsthatinteractedwithanAPCsupportedtheideathatIFN-productionbyTcellscouldbeinducedbyintermittentsignals(7).Dependingonthesystemused,reexposureofinvitroactivatedCD4TcellstoAgcansustaincellproliferation,promoteIFN-production,orinducecelldeath(8,9).In...
参考资料医源资料库;在线期刊;实验医学杂志;2005年第202卷第9期...eviously.30CXCR4receptorexpressionwasdeterminedbyanti-humanallophycocyanin(APC)-labeledantibody(BDPharmingen)andanantibodyagainstepitope6H8,whichrecognizesanepitopelocatedbetweenresidues22and25oftheN-terminalextracellulardomainoftheCXCR4receptor(kindlyprovidedbyDr.Arenzana-Seisdesdos,PasteurInstitut...
参考资料医源资料库;在线期刊;循环研究杂志;2005年第95卷第11期...,DC)是一类重要的专职抗原提呈细胞(Antigen-presentingcells,APC),具有活化幼稚T淋巴细胞的功能,同时自身又高表达主要组织相容性复合体(MHC)Ⅱ类分子。Kohn等[3]使用电子显微镜发现正常表皮内27%的郎格罕细胞接近基底层,65%位于表皮...
参考资料医源资料库;在线期刊;中华现代临床医学杂志;2012年第10卷第6期...andmouseanti-CD3PE(bothfromPharmingen,SanDiego,CA),andF4/80allophycocyanin(APC)andF4/80PE(bothfromCaltag,BotolphClaydon,UK).Cellnumberwasdeterminedasdescribedpreviously(27).AdoptiveTransferofPleuralCellPopulationsPleurallavagesfromgroupsofnaiveFVB/NWTmicewereincubatedwithPE-conjugatedanti-F4/80antib...
参考资料医源资料库;在线期刊;美国呼吸和危急护理医学;2006年第173卷第5期...ysymptoms,nopasthistoryofASAhypersensitivity,anFEV1greaterthan80%predicted,aPC20methacholinegreaterthan25mg/ml,andnormalfindingsonasimplechestradiogram.Allsubjectsgaveinformedconsent,andtheprotocolswereapprovedbythelocalethicscommittees.AspirinChallengeandSeparationofPlasmaOralaspirinchallengewasper...
参考资料医源资料库;在线期刊;美国呼吸和危急护理医学;2006年第173卷第4期...mamembraneortargetedforproteosomaldegradationbytheadenomatouspolyposiscoli(APC),Axin,andglycogensynthasekinase3?(GSK3?)complex.However,inthepresenceofWntsignaling,theAPC-Axin-GSK3?complexisinhibitedbecauseofinactivationofGSK-3?byWnt.Thisresultsinincreasedfreecytoplasmic?-catenin,whichtranslocatestot...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第7期...armLyse(BectonDickinson).Cellswereincubatedwiththefollowingantibodies:CD19-APC,CD27-PE(Caltag),anti-FcRIIB(asdescribedinthepreviousparagraph),mouseIgG1controlantibody,andgoatanti–mouseIgG1(BDBiosciences).FlowcytometryfortheSLEsubjectsandthecontrolAgroupwasperformedwithaFACSCalibur(BectonDickinson)...
参考资料医源资料库;在线期刊;实验医学杂志;2006年第203卷第9期...sofvascularobliterationandneovasculartuftswerequantifiedfromthesemontages.NAPc2,NAP5,andImatinibTreatmentImmediatelyafterreturntonormoxiaatdayP12,miceweretreatedwithintraperitonealinjectionsofNAPc2(1mg/kg)orascontrolswitheitherbufferornonreactiveantibody.DosingwasoncedailyuntilsacrificeatdayP17.NAP5...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第6期...形成的遗传或获得性的生物化学因素,包括活化蛋白C(APC)抵抗,高半胱氨酸血症,抗凝血酶缺乏,蛋白C缺乏,蛋白S缺乏,抗磷脂抗体(抗心肌磷脂抗体,狼疮抗凝剂)。当权衡利弊时,医生应考虑到对一种病情的适当治疗可...
药品说明书药品说明书...athperfusion(1ml/min)withadeadtimeof1020s.CurrentrecordingswereacquiredwithaPC505Bpatch-clampamplifier(WarnerInstruments)interfacedviaaDigidata1322A(AxonInstruments)toaPCrunningthepClamp9suiteofsoftware(AxonInstruments).Forexcisedpatches,gap-freecurrentrecordingsweremadeat0mV.Forwholecellexperiments...
参考资料医源资料库;在线期刊;美国生理学杂志;2005年第288卷第1期