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  • NicotineInducesProinflammatoryResponsesinMacrophagesandtheAortaLeadingtoAccelerationofAtherosclerosisinLow-DensityLipoproteinReceptor-/-Mic

    【摘要】Objective-Weinvestigatedthemolecularmechanismofnicotine-acceleratedatherosclerosisinahyperlipidemiclow-densitylipoproteinreceptor-/-mousemodel.MethodsandResults-Low-densitylipoproteinreceptor-/-micereceivedtime-releasenicotineorplacebopelletsfor90days.Aorticlesionsizewas2.5timeslargerinn...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第1期
  • 10.4病理生理学

    ...增高。目前尚无证据说明脂肪肝在患者早期可发展成为肝硬化或肝癌。  血脂:消瘦型患者浆中甘油三酯、胆固醇、β-脂蛋白含量正常或增高。但有的资料指出,血浆中甘油三酯浓度增高,而总胆固醇、γ-和β-脂蛋白固醇和磷...

    参考资料医源资料库;医源图书馆;教材类;临床营养学
  • PhospholipidHydroxyalkenals

    Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—Phosphatidylcholinehydroxyalkenals(PC-HAs)areaclassofoxidizedPCsderivedfromlipidperoxidationofarachidonateorlinoleateatthesn-2positiontoformterminal-hydroxy,-,andß-unsaturatedaldehydes.Theaimofthisstudywastochar...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期
  • (6R)-5,6,7,8-Tetrahydro-L-BiopterinandItsStereoisomerPreventIschemiaReperfusionInjuryinHumanForearm

    【摘要】Objective—6R-5,6,7,8-tetrahydro-L-biopterin(6R-BH4)isacofactorforendothelialnitricoxidesynthasebutalsohasantioxidantproperties.Itsstereo-isomer6S-5,6,7,8-tetrahydro-L-biopterin(6S-BH4)andstructurallysimilarpterin6R,S-5,6,7,8-tetrahydro-D-neopterin(NH4)arealsoantioxidantsbuthavenoco...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第6期
  • ThrombinActivatableFibrinolysisInhibitorActivationPeptideShowsAssociationWithAllMajorSubtypesofIschemicStrokeandWithTAFIGeneVariation

    【摘要】Objective-Thrombinactivatablefibrinolysisinhibitor(TAFI)attenuatesfibrinolysis.TheaimofthepresentstudywastoinvestigatethepossibleassociationbetweenTAFIandoverallischemicstrokeandischemicstrokesubtypes.MethodsandResults-TheSahlgrenskaAcademyStudyonIschemicStroke(SAHLSIS)comprises600cases(...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期
  • PioglitazoneInhibitsIn-StentRestenosisinAtheroscleroticRabbitsbyTargetingTransformingGrowthFactor-ßandMCP-

    【摘要】Objective-Althoughemergingdatafrompreclinicalandclinicalstudiessuggestsareductionofin-stentrestenosiswithperoxisomeproliferator-activatedreceptor(PPAR)-agonists,thereductionofneointimalgrowthviaanti-inflammatorymechanismshasnotbeenexplored.MethodsandResults-HypercholesterolemicNewZealand...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期
  • AssociationBetweenSerumUricAcid,MetabolicSyndrome,andCarotidAtherosclerosisinJapaneseIndividuals

    FromtheDepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofMedicine(N.I.,R.N.),andCenterforMultiphasicHealthTestingandServices,MitsuiMemorialHospital(Y.I.,E-I.T.,M.Y.),Tokyo,Japan.CorrespondencetoDrNobukazuIshizaka,DepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofM...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第5期
  • AtherosclerosisIsAttenuatedbyLimitingSuperoxideGenerationinBothMacrophagesandVesselWallCells

    【摘要】Objective—WepreviouslyshowedthatNAD(P)HoxidasedeficiencysignificantlyreducesatherosclerosisinapoE–/–mice.Thepresentstudywasdesignedtodeterminetherelativecontributionofmonocyte/macrophageversusvascularwallcellNAD(P)Hoxidasetoatherogenesisinthismodel.MethodsandResults&mda...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期
  • M-CSFAcceleratesNeointimalFormationintheEarlyPhaseAfterVascularInjuryinMice

    【摘要】Objective-Sincethemacrophagecolony-stimulatingfactor(M-CSF)hasbeenshowntostimulatedifferentiationandproliferationofmonocyte/macrophagelineageandtobeinvolvedintheprocessofneointimalformationaftervascularinjury,wetestedtheeffectsofM-CSFontherecruitmentofbonemarrow-derivedprogenitorcellsinn...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第2期
  • Weight-RelatedIncreasesinHypertension,Hypercholesterolemia,andDiabetesRiskinNormalWeightMaleandFemaleRunners

    【摘要】Background-Although36%ofUSmenand42%ofUSwomenareofnormalweight,thehealthimplicationsofgreaterweightinostensiblynormal-weightindividualsareseldomacknowledged.MethodsandResults-Self-reportedphysician-diagnosedincidentdiabetes,highcholesterol,andhypertensionwerecomparedwithadultbodymassindex...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第8期

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