【摘要】Objective-Weinvestigatedthemolecularmechanismofnicotine-acceleratedatherosclerosisinahyperlipidemiclow-densitylipoproteinreceptor-/-mousemodel.MethodsandResults-Low-densitylipoproteinreceptor-/-micereceivedtime-releasenicotineorplacebopelletsfor90days.Aorticlesionsizewas2.5timeslargerinn...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第1期...增高。目前尚无证据说明脂肪肝在患者早期可发展成为肝硬化或肝癌。 血脂:消瘦型患者浆中甘油三酯、胆固醇、β-脂蛋白含量正常或增高。但有的资料指出,血浆中甘油三酯浓度增高,而总胆固醇、γ-和β-脂蛋白固醇和磷...
参考资料医源资料库;医源图书馆;教材类;临床营养学Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—Phosphatidylcholinehydroxyalkenals(PC-HAs)areaclassofoxidizedPCsderivedfromlipidperoxidationofarachidonateorlinoleateatthesn-2positiontoformterminal-hydroxy,-,andß-unsaturatedaldehydes.Theaimofthisstudywastochar...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期【摘要】Objective—6R-5,6,7,8-tetrahydro-L-biopterin(6R-BH4)isacofactorforendothelialnitricoxidesynthasebutalsohasantioxidantproperties.Itsstereo-isomer6S-5,6,7,8-tetrahydro-L-biopterin(6S-BH4)andstructurallysimilarpterin6R,S-5,6,7,8-tetrahydro-D-neopterin(NH4)arealsoantioxidantsbuthavenoco...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第6期【摘要】Objective-Thrombinactivatablefibrinolysisinhibitor(TAFI)attenuatesfibrinolysis.TheaimofthepresentstudywastoinvestigatethepossibleassociationbetweenTAFIandoverallischemicstrokeandischemicstrokesubtypes.MethodsandResults-TheSahlgrenskaAcademyStudyonIschemicStroke(SAHLSIS)comprises600cases(...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期【摘要】Objective-Althoughemergingdatafrompreclinicalandclinicalstudiessuggestsareductionofin-stentrestenosiswithperoxisomeproliferator-activatedreceptor(PPAR)-agonists,thereductionofneointimalgrowthviaanti-inflammatorymechanismshasnotbeenexplored.MethodsandResults-HypercholesterolemicNewZealand...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期FromtheDepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofMedicine(N.I.,R.N.),andCenterforMultiphasicHealthTestingandServices,MitsuiMemorialHospital(Y.I.,E-I.T.,M.Y.),Tokyo,Japan.CorrespondencetoDrNobukazuIshizaka,DepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofM...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第5期【摘要】Objective—WepreviouslyshowedthatNAD(P)HoxidasedeficiencysignificantlyreducesatherosclerosisinapoE–/–mice.Thepresentstudywasdesignedtodeterminetherelativecontributionofmonocyte/macrophageversusvascularwallcellNAD(P)Hoxidasetoatherogenesisinthismodel.MethodsandResults&mda...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期【摘要】Objective-Sincethemacrophagecolony-stimulatingfactor(M-CSF)hasbeenshowntostimulatedifferentiationandproliferationofmonocyte/macrophagelineageandtobeinvolvedintheprocessofneointimalformationaftervascularinjury,wetestedtheeffectsofM-CSFontherecruitmentofbonemarrow-derivedprogenitorcellsinn...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第2期【摘要】Background-Although36%ofUSmenand42%ofUSwomenareofnormalweight,thehealthimplicationsofgreaterweightinostensiblynormal-weightindividualsareseldomacknowledged.MethodsandResults-Self-reportedphysician-diagnosedincidentdiabetes,highcholesterol,andhypertensionwerecomparedwithadultbodymassindex...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第8期