【摘要】Vascularcalcificationincreasinglyafflictsouraginganddysmetabolicpopulation.Onceconsideredapassiveprocess,ithasemergedasanactivelyregulatedformofcalcifiedtissuemetabolism,resemblingthemineralizationofendochondralandmembranousbone.Executivecelltypesfamiliartobonebiologists,osteoblasts,chon...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期FromtheDepartmentsofChemistryandChemicalBiology(E.M.M.,R.J.L.)andChemicalandBiologicalEngineering(R.J.L.),DepartmentofBiology,RensselaerPolytechnicInstitute,Troy,NY.ABSTRACTHeparinisamajoranticoagulantwithactivitymediatedprimarilythroughitsinteractionwithantithrombin(AT).Heparansulfate(HS),structura...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第9期FromtheDepartmentofCellBiologyNC10,ClevelandClinicFoundation,Cleveland,Ohio.ABSTRACTObjective—ABCA1mediatescellularcholesterolandphospholipideffluxtoapolipoproteinA-Iandotherapolipoproteinacceptors.Inthisstudy,weanalyzedtheeffectoftheimmunosuppressantcyclosporinAontheABCA1-mediatedlipideffluxesrea...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第11期【摘要】Objective-AfunctionalpolymorphisminthechemokinereceptorCX3CR1isassociatedwithprotectionfromvasculardiseasesincludingcoronaryarterydiseaseandinternalcarotidarteryocclusivedisease.WeinvestigatedthemechanismsbywhichCX3CR1maybeinvolvedbyevaluatingtheinflammatoryresponsetoarterialinjuryinCX3C...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第9期【摘要】Objective-TostudytheacceptorspecificityforhumanABCG1(hABCG1)-mediatedcholesterolefflux.MethodsandResults-CellsoverexpressinghABCG1werecreatedinChineseHamsterOvary(CHO-K1)cellsandcharacterizedintermsoflipidcomposition.hABCG1expressedinthesecellsformedhomodimersandwasmostlypresentintracell...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第3期FromtheWihuriResearchInstitute,Helsinki,Finland.ABSTRACTThe2majorgeneralconceptsaboutthecellbiologyofatherogenesis,growthofsmoothmusclecells,andlipidaccumulationinmacrophages,ie,foamcellformation,havenotbeenabletosatisfactorilyexplainthegenesisofacutecoronarysyndromes.Rather,thebasicpathologybehindt...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第8期FromtheDivisionofClinicalPharmacology,DepartmentsofMedicineandPharmacology,VanderbiltUniversitySchoolofMedicine,NashvilleTenn.CorrespondencetoJasonD.Morrow,MD,526RRB,23rdandPierceAve,VanderbiltUniversity,Nashville,TN37232-6602.E-mailjason.morrow@vanderbilt.eduAbstractEnhancedoxidantstressoccurringei...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第2期【摘要】Objective-Theacquisitionofarterialorvenousidentityishighlightedinvasculardevelopment.Previously,wehavereportedanembryonicstem(ES)celldifferentiationsystemthatexhibitsearlyvasculardevelopmentusingvascularendothelialgrowthfactor(VEGF)receptor-2(VEGFR2)-positivecellsascommonvascularprogenit...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第9期【摘要】Objective-Previousstudiesdemonstratedthatobeseadiposetissueischaracterizedbyincreasedinfiltrationofmacrophages,suggestingthattheymightrepresentanimportantsourceofinflammation.Usinganinvitrococulturesystemcomposedof3T3-L1adipocytesandRAW264macrophages,wepreviouslydemonstratedthatsaturated...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第1期FromtheInstituteofPhysiology(F.K.,U.P.)andCardiologyDivision(F.K.,H.-Y.S.),MedizinischePoliklinik-Innenstadt,Ludwig-Maximilians-University,Munich,Germany.ABSTRACTPlateletsparticipatenotonlyinthrombusformationbutalsointheregulationofvesseltone,thedevelopmentofatherosclerosis,angiogenesis,andinneointi...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第11期