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  • ExtracellularSignal-RegulatedKinase–DependentStabilizationofHepaticLow-DensityLipoproteinReceptormRNAbyHerbalMedicineBerberine

    FromtheVAPaloAltoHealthCareSystem(P.A.,Y.Z.,J.L.),PaloAlto,Calif;andInstituteofMedicinalBiotechnology(J.-D.J.),ChineseAcademyofMedicalSciences,Beijing,China.CorrespondencetoJingwenLiu,PhD,VAPaloAltoHealthCareSystem,3801MirandaAve,PaloAlto,CA94304.E-mailJingwen.Liu@med.va.govAbstractObjective—Ourre...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第10期
  • DecreasedAtherosclerosisinLow-DensityLipoproteinReceptorKnockoutMiceTransplantedWithAbcg1-/-BoneMarrow

    【摘要】Objective-RecentstudiesindicatethattheATP-bindingcassettetransporterABCG1canpromotecholesteroleffluxfrommacrophagestohigh-densitylipoprotein.ThisstudywasdesignedtoassesstheinvivoroleofmacrophageABCG1inatherosclerosis.MethodsandResults-BonemarrowfromAbcg1-/-micewastransplantedintoirradiat...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第10期
  • EndotoxinInducesToll-LikeReceptor4ExpressioninVascularSmoothMuscleCellsviaNADPHOxidaseActivationandMitogen-ActivatedProteinKinaseSignaling

    【摘要】Objective-Toll-likereceptor4(TLR4)playsamajorrolemediatingendotoxin-inducedcellularinflammationandregulatesvascularsmoothmusclecell(VSMC)proliferation,whichisrelatedtoatherogenesisandrestenosis.Thisstudywasconductedtoinvestigatethemechanismsinvolvedinlipopolysaccharide(LPS)-inducedTLR4ex...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期
  • PharmacologicalInhibitionandGeneticDeficiencyofPlasminogenActivatorInhibitor-1AttenuatesAngiotensinII/Salt-InducedAorticRemodeling

    FromtheDepartmentofMedicine,DivisionsofClinicalPharmacology(A.D.W.,J.P.G.,N.J.B.)andCardiovascularMedicine(F.A.,D.E.V.)andtheDepartmentofPathology(A.B.F.),VanderbiltUniversityMedicalCenter,Nashville,Tenn;CardiovascularandMetabolicDiseasesResearch(D.L.C.,H.E.),WyethResearch,Collegeville,Pa.Correspond...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第2期
  • LeukocyteTransglutaminase2ExpressionLimitsAtheroscleroticLesionSize

    【摘要】Objective-Transglutaminase2(TG2),abroadlyexpressedregulatorofproteincross-linking,woundhealing,andtissuefibrosis,mediatesapoptoticcellingestionandtransforminggrowthfactor-ßreleasebymacrophagesandtherebycanlimitleukocyte-mediatedinflammation.Inatherosclerosis,oxidativestressandaccum...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第3期
  • TherapeuticPotentialofaSyntheticPeptideInhibitorofNuclearFactorofActivatedTCellsasAntirestenoticAgent

    【摘要】Objective-Thecalcineurin/nuclearfactorofactivatedTcells(NFAT)axisplaysapivotalroleintheregulationofcriticalgenesinvascularsmoothmusclecell(vSMC)proliferationandinflammation,whichmakesNFATinhibitionanattractivemodalityinthepreventionofrestenosis.MethodsandResults-SyntheticpeptideVIVITpote...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第7期
  • Glucosamine-InducedEndoplasmicReticulumStressPromotesApoB100Degradation

    FromtheDivisionofClinicalBiochemistry(W.Q.,R.K.-A.,S.M.,J.T.,K.A.),theDepartmentofLaboratoryMedicinePathobiology,HospitalforSickChildren,UniversityofToronto,Ontario,Canada;andtheDepartmentofPathologyandMolecularMedicine(R.C.A.),McMasterUniversity,Hamilton,Ontario,Canada.CorrespondencetoKhosrowAdeli,...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第3期
  • AtherogenesisinMiceDoesNotRequireCD40LigandFromBoneMarrow–DerivedCells

    FromDonaldW.ReynoldsCardiovascularClinicalResearchCenter(U.B.,A.Z.,S.L.,L.M.,P.L.,U.S.),DepartmentofMedicine,BrighamandWomen’sHospital,HarvardMedicalSchool,Boston,Mass;andCardiologyAngiology(U.B.),HannoverMedicalSchool,Germany.CurrentaffiliationforUweSch?nbeck:BoehringerIngelheimPharmaceuticalInc,...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第6期
  • SecretoryPhospholipaseA2GroupV

    【摘要】Objective-TostudythedistributionofgroupVsecretoryphospholipaseA2(sPLA2)inhumanandmouselesionsandcompareitsexpressionbyhumanvascularcells,itsactivitytowardlipoproteins,andtheinteractionwitharterialproteoglycans(proteoglycans)withthoseofsPLA2-IIA.Inaddition,wealsoinvestigatedtheeffectofaWe...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第7期
  • HighGlucoseActivatesNuclearFactorofActivatedTCellsinNativeVascularSmoothMuscle

    【摘要】Objective-Hyperglycemiahasbeensuggestedtoplayaroleinthedevelopmentofvasculardiseaseassociatedwithdiabetes.AtypicalCa2+signalingandgeneexpressionarecharacteristicofvasculardysfunction;however,littleisknownregardingtheeffectsofhighglucoseonCa2+-dependenttranscriptioninthevascularwall.Metho...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第4期

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