【摘要】Objective—Previousstudieshaveindicatedthatthehyperlipidemiaandgeneexpressionchangesinducedbyashort-termhigh-fatdiet(HFD)aremediatedthroughtheperoxisomeproliferator-activatedreceptorcoactivator(PGC)-1β,andthatinvitrobothPGC-1βandPGC–1increasePPAR-mediatedtranscriptio...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第12期FromVascularMedicineResearch,BrighamWomen’sHospitalandHarvardMedicalSchool,Cambridge,Mass.ABSTRACTObjective—Todeterminetheroleofthecardiovascular-restricted,hairy-relatedbHLHtranscriptionfactor,CHF1/Hey2,inthebiologicalresponsetovascularinjury.MethodsandResults—WeinvestigatedtheresponseofCHF1/...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第11期【摘要】Objective-Lipopolysaccharide(LPS)interactswithtoll-likereceptor4(TLR4)andinducesproliferationofvascularsmoothmusclecells(VSMCs)whichplaysacausalroleinatherogenesis.TheroleofTLR4expressionandregulationinLPS-stimulatedVSMCsremainsunclear.TLR4mRNAsoftencontainAU-richelements(AREs)intheir3...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第12期*Representingthefollowingparticipatingorganizationsandmajorcosponsors:theAmericanHeartAssociation;AmericanCollegeofCardiology;AmericanCollegeofNursePractitioners;AmericanCollegeofObstetriciansandGynecologists||;AmericanCollegeofPhysicians?;AmericanMedicalWomen’sAssociation#;AssociationofBlackCardi...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第3期【摘要】Objective—Obesityisrecognizedincreasinglyasamajorriskfactorforkidneydisease.Wereportedpreviouslythatplasmaadiponectinlevelsweredecreasedinobesity,andthatadiponectinhaddefensivepropertiesagainsttype2diabetesandhypertension.Inthisstudy,weinvestigatedtheroleofadiponectinforkidneydisea...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第9期FromtheDavidGeffenSchoolofMedicineatUCLA(M.N.,S.T.R.,S.H.,G.H.,V.R.G.,N.Y.,B.J.A.,A.M.F.),LosAngeles,Calif;andtheDepartmentofMedicine(G.M.A.,G.D.,D.W.G.),AtherosclerosisResearchUnit,UniversityofAlabama,Birmingham.CorrespondencetoDrMohamadNavab,Room47-123CHS,DivisionofCardiology,DepartmentofMedicine,...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第7期【摘要】Objective-Tostudymatrixmetalloproteinase2(MMP-2)effectsontransforminggrowthfactor-ß1(TGF-ß1)activationstatusanddownstreamsignalingduringarterialaging.MethodsandResults-WesternblottingandimmunostainingshowedthatlatentandactivatedTGF-ß1aremarkedlyincreasedwithintheaortaof...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期Endothelialdysfunctionisasystemicdisorderandakeyvariableinthepathogenesisofatherosclerosisanditscomplications.Currentevidencesuggeststhatendothelialstatusisnotdeterminedsolelybytheindividualriskfactorburdenbutrather,mayberegardedasanintegratedindexofallatherogenicandatheroprotectivefactorspresentina...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2003年第23卷第2期FromtheDepartmentofVeterinaryPharmacology,GraduateSchoolofAgricultureandLifeSciences,TheUniversityofTokyo,Japan.CorrespondencetoMasatoshiHori,PhD,DepartmentofVeterinaryPharmacology,GraduateSchoolofAgricultureandLifeSciences,TheUniversityofTokyo,1-1-1Yayoi,Bunkyo-ku,Tokyo113-8657,Japan.E-mailahori@ma...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第2期【摘要】Objective-Theactivityoftheantitumoralagentbexarotene(Targretin,Bexarotene)dependsonitsbindingtothenuclearretinoid-Xreceptor(RXR)andsubsequenttranscriptionalregulationoftargetgenes.ThroughRXRactivation,bexarotenemaymodulatenumerousmetabolicpathwaysinvolvedinatherosclerosis.Here,weinvestig...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第12期