【摘要】Objective-ThisworkwasundertakentoinvestigatecomparativeeffectofAT1receptorblocker(ARB),3-hydroxy-3-methylglutaryl(HMG)coenzymeA(CoA)reductaseinhibitor(statin),andtheircombinationonvascularinjuryofsalt-sensitivehypertension.MethodsandResults-Salt-loadedDahlsalt-sensitivehypertensiverats(D...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第3期FromtheDepartmentofCardiology,FukuokaUniversitySchoolofMedicine,Fukuoka,Japan.ABSTRACTBackground—Inhibitionofcholesterylestertransferprotein(CETP)isanefficientwaytoincreasehigh-densitylipoprotein(HDL)levelsinhumans.WeinvestigatedtheeffectsoftheinhibitionofCETPactivitybyaCETPinhibitor,JTT-705,onthe...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第10期FromtheDivisionofMolecularMedicine(S.B.S.,A.R.T.,C.L.W.),theDepartmentofMedicine,InstituteofHumanNutrition(S.B.S.,C.D.L.,R.L.L.,A.R.T.),andtheDivisionofMolecularGenetics(C.D.L.,R.L.L.),DepartmentofPediatrics,ColumbiaUniversity,NewYork;andtheLaboratoryofBiochemicalGeneticsandMetabolism(J.L.B.),TheRoc...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第1期【摘要】Objective-GroupVsecretoryphospholipaseA2(GVsPLA2)hasbeendetectedinbothhumanandmouseatheroscleroticlesions.Thisenzymehaspotenthydrolyticactivitytowardsphosphatidylcholine-containingsubstrates,includinglipoproteinparticles.Numerousstudiesinvitroindicatethathydrolysisofhighdensitylipoprotei...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第3期【摘要】Objective-Collateralarterydevelopment(arteriogenesis),avitalcompensatorymechanisminpatientswitharterialobstructivedisease,maybederegulatedbyvascularriskfactors,eg,diabetesorhypercholesterolemia.Here,wecomparedtheeffectsofeitherdisturbedglucosemetabolismordisturbedlipidmetabolismonarterio...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第6期AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective—AngiotensinII(AII)hasbeenshowntoincreaseendothelialNAD(P)Hoxidaseactivity,whichisasourceofsuperoxideanionthatinturnmayinducetheformationofperoxynitrite.Estrogen(E2)hasbeenreportedtohavevascularprotectiveeffects.Inthisstudy,...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2003年第23卷第1期FromtheDepartmentofInternalMedicine,UniversityofKentuckyMedicalCenter,Lexington,Kentucky.ABSTRACTObjectives—SecretoryphospholipaseA2(sPLA2)enzymeshydrolyzethesn-2fattyacylesterbondofphospholipidstoproduceafreefattyacidandalysophospholid.GroupVsPLA2isexpressedinculturedmacrophagecellsandhashighaffi...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第4期FromtheHemostasisandThrombosisResearchCentre,DepartmentofHematology,LeidenUniversityMedicalCentre,Leiden,theNetherlands.ABSTRACTObjective—ItisgenerallyassumedthatC-reactiveprotein(CRP)inducessynthesisoftissuefactor(TF)inmonocyticcells,therebypotentiallyinitiatingintravascularbloodcoagulation.Weaim...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第5期FromtheDepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofMedicine(N.I.,R.N.),andCenterforMultiphasicHealthTestingandServices,MitsuiMemorialHospital(Y.I.,E-I.T.,M.Y.),Tokyo,Japan.CorrespondencetoDrNobukazuIshizaka,DepartmentofCardiovascularMedicine,UniversityofTokyoGraduateSchoolofM...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第5期FromX-CeptorTherapeuticsInc,SanDiego,Calif.CorrespondencetoIraG.Schulman,PhD,X-CeptorTherapeuticsInc,4757NexusCenterDrive,Suite200,SanDiego,CA92121.E-mailischulman@exelixis.comAbstractObjective—Complicationsofatheroscleroticcardiovasculardiseaseduetoelevatedbloodcholesterollevelsarethemajorcauseof...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第1期