【摘要】Objective—Vascularendothelialgrowthfactor(VEGF),akeyangiogenicgrowthfactor,stimulatesangiogenesis.Lowlevelsofreactiveoxygenspecies(ROS)functionassignalingmoleculesforangiogenesis.WepostulatedthatlowconcentrationsofoxLDLmightinducelowlevelsofROSandinitiateangiogenesis.MethodsandResu...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第11期【摘要】Objective—6R-5,6,7,8-tetrahydro-L-biopterin(6R-BH4)isacofactorforendothelialnitricoxidesynthasebutalsohasantioxidantproperties.Itsstereo-isomer6S-5,6,7,8-tetrahydro-L-biopterin(6S-BH4)andstructurallysimilarpterin6R,S-5,6,7,8-tetrahydro-D-neopterin(NH4)arealsoantioxidantsbuthavenoco...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第6期【摘要】Objective-AngiotensinII(AngII)disruptstheregulationofthecerebralcirculationthroughsuperoxide,areactiveoxygenspecies(ROS)generatedbyanox2-containingNADPHoxidase.WetestedthehypothesisthatAngII-derivedsuperoxidereactswithnitricoxide(NO)toformperoxynitrite,which,inturn,contributestothevascul...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第2期FromtheDepartmentofMedicine,SamsungMedicalCenter,SamsungBiomedicalResearchInstitute,SungkyunkwanUniversitySchoolofMedicine,Seoul,Korea.ABSTRACTObjective—Increasedriskofcardiovasculardiseaseinpatientswithchronicrenalfailure(CRF)hasbeenexplainedbyacceleratedatherosclerosisandimpairedangiogenesis,inw...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第7期FromtheLipidResearchLaboratory,TechnionFacultyofMedicine(M.R.,T.H.,K.H.,M.A.),TheRappaportFamilyInstituteforResearchintheMedicalSciencesandRambamMedicalCenter,andtheInternalMedicineDepartment(H.T.,H.K.),RambamMedicalCenter,Haifa,Israel.CorrespondencetoProf.MichaelAviram,D.Sc,TheLipidResearchLaborato...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第1期【摘要】Objective-Recentevidencesuggeststhatdendriticcellsmayplayanimportantroleinatherosclerosis.Basedprimarilyonpreviousinvitrostudies,wehypothesizedthatgranulocytemacrophagecolony-stimulatingfactor(GM-CSF)-deficientmicewouldhavedecreaseddendriticcellsinlesions.MethodsandResults-Totestthis,wec...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第3期FromtheDepartmentofBiomedicalSciences(C.P.O.,P.T.,S.C.),UniversityofModenaandReggioEmilia;DepartmentofInternalMedicine(L.P.,A.B.,S.B.),UniversityofGenova;DepartmentofPediatrics(G.L.V.,M.P.S.),UniversityofCatania;NationalInstituteofHealth(A.C.),Rome;DepartmentofPharmacologicalSciences(A.C.),Universit...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第2期【摘要】Objective-Thromboembolizationandsubsequentmicrovascularperfusionfailureisimplicatedinthepathologyofavarietyofdiseases,includingtransientischemicattack(TIA),stroke,andmyocardialinfarction,andalsoforthecomplicationsafterinterventionalandmicrosurgicalproceduresincoronaryheartdiseaseandperip...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期FromtheDepartmentsofMedicine(C.M.D.,G.K.,C.K.,L.S.H.,I.T.)andAnatomyCellBiology(I.T.)andPhysiologyCellularBiophysics(I.T.),ColumbiaUniversity,NewYork,NY;theDivisionofFoodScience(S.J.L.),CollegeofLifeandEnvironmentalSciences,KoreaUniversity,Seoul,Korea;theDepartmentofMedicine(S.J.L.,I.G.,A.D.C.),Stan...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第8期【摘要】Background-Themetabolicsyndromeistypifiedbyobesity,dyslipidemia,diabetes,hypertension,increasedoxidativestress,andacceleratedatherosclerosis.Paraoxonase1(PON1),ahigh-densitylipoprotein(HDL)-associatedantioxidantenzymethatpreventstheoxidationoflow-densitylipoprotein(LDL),islowinthemetabol...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期