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  • MicroarrayAnalysisRevealsOverexpressionofCD163andHO-1inSymptomaticCarotidPlaques

    【摘要】Objective-Westudiedbymicroarrayanalysiswhethersymptomaticandasymptomaticcarotidplaquesfromthesamepatientdifferingeneexpressionandwhetherthesamechangesarepresentinanindependentsampleset.MethodsandResults-Carotidplaquesfromfourpatientswithbilateralhigh-gradestenosis,onebeingsymptomaticandt...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期
  • Hyplip2,aNewGeneforCombinedHyperlipidemiaandIncreasedAtherosclerosis

    FromtheDepartmentsofMedicine,Microbiology,Immunology,andMolecularGenetics,andHumanGenetics(X.Wang,P.G.,J.W.,X.Wu,H.Q.,P.W.,L.W.C.,A.J.L.),UniversityofCalifornia,LosAngeles;theDivisionofBiology(J.L.G.),CaliforniaInstituteofTechnology,Pasadena;andtheDepartmentofCardiovascularMolecularSciencesandTechno...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期
  • InVivoLow-DensityLipoproteinExposureInducesIntercellularAdhesionMolecule-1andVascularCellAdhesionMolecule-1CorrelatedWithActivatorProtein-1E

    【摘要】Objective-Wetestedthehypothesisthatdirectnativelow-densitylipoprotein(LDL)injectionintoLDLreceptor-deficient(LDLR-/-)micewouldinducetheadhesionmoleculesintercellularadhesionmolecule-1(ICAM-1)andvascularcelladhesionmolecule-1(VCAM-1)intheiraorticendothelialcells,andthattranscriptionalregu...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第6期
  • InsulinSignalinginArteriesPreventsSmoothMuscleApoptosis

    FromtheNationalCardiovascularCenterResearchInstitute(T.N.,T.C.,K.S.),Osaka;FirstInstituteofNewDrugDiscovery,OtsukaPharmaceuticalCo.,Ltd.(T.N.),Tokushima;andTokyoMedicalandDentalUniversityGraduateSchool(T.N.,T.C.,E.K.,K.Y.,M.Y.,K.S.),Tokyo,Japan.CorrespondencetoKentaroShimokado,MD,GeriatricsandVascul...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第4期
  • IncreasedConcentrationsofC-ReactiveProteinandIL-6butnotIL-18AreIndependentlyAssociatedWithIncidentCoronaryEventsinMiddle-AgedMenandWomen

    【摘要】Objectives-Weperformedaprospectivecase-cohortstudyininitiallyhealthy,middle-agedmenandwomenfromtheMONICA/KORAAugsburgstudiesconductedbetween1984and2002toassesstheroleofIL-18incomparisonwithIL-6andCRPinthepredictionofincidentcoronaryheartdisease(CHD).MethodsandResults-ConcentrationsofIL-1...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期
  • HypochlorousAcid,aMacrophageProduct,InducesEndothelialApoptosisandTissueFactorExpression

    SeigoSugiyama;KiyotakaKugiyama;MasanoriAikawa;ShinichiNakamura;HisaoOgawa;PeterLibbyFromtheLeducqCenterforCardiovascularResearch(S.S.,M.A.,P.L.),BrighamandWomen’sHospital,HarvardMedicalSchool,Boston,Mass;theDepartmentofCardiovascularMedicine(S.S.,S.N.,H.O.),GraduateSchoolofMedicalSciences,Kumamoto...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第7期
  • OxidativeStressPromotesEndothelialCellApoptosisandLossofMicrovesselsintheSpontaneouslyHypertensiveRats

    FromtheDepartmentofBioengineering,WhitakerInstituteofBiomedicalEngineering,UniversityofCalifornia,SanDiego,LaJolla,Calif.CorrespondencetoDrGeertW.Schmid-Sch?nbein,DepartmentofBioengineering,WhitakerInstituteofBiomedicalEngineering,UniversityofCalifornia,SanDiego,9500GilmanDrive,LaJolla,CA92093-0412....

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第10期
  • MacrophageLow-DensityLipoproteinReceptor-RelatedProteinDeficiencyEnhancesAtherosclerosisinApoE/LDLRDoubleKnockoutMice

    【摘要】Objective-Invitrostudiesimplicatethatthelow-densitylipoproteinreceptor(LDLR)-relatedprotein(LRP)inmacrophageshasapro-atherogenicpotential.Inthepresentstudy,weinvestigatedtheinvivoroleofmacrophagespecificLRPinatherogenesisindependentofitsroleintheuptakeoflipoproteins.MethodsandResults-Weg...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期
  • EndocytosisofExtracellularSuperoxideDismutaseIntoEndothelialCells

    【摘要】Objective-Extracellularsuperoxidedismutase(EC-SOD)isasecretedantioxidantenzymethatbindstotheouterplasmamembraneandextracellularmatrixthroughitsheparin-bindingdomain(HBD).CarriersofacommongeneticvariantofEC-SOD(EC-SODR213G,withintheHBD)havehigherplasmaconcentrationofEC-SODandincreasedrisk...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第9期
  • DietaryFat–InducedAlterationsinAtherosclerosisAreAbolishedbyACAT2-DeficiencyinApoB100Only,LDLr–/–Mice

    【摘要】Objectives—Theenzymeacyl-coenzymeA(CoA):cholesterolO-acyltransferase2(ACAT2)intheliversynthesizescholesterylesters(CE)fromcholesterolandfattyacyl-CoA,whichgetincorporatedintoapoB-containinglipoproteinsthataresecretedintothebloodstream.Dietaryfattyacidcompositioninfluencestheamounta...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第6期

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