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  • CD44RegulatesVascularGeneExpressioninaProatherogenicEnvironment

    【摘要】Objective-ToidentifyearlychangesinvasculargeneexpressionmediatedbyCD44thatpromoteatheroscleroticdiseaseinapolipoproteinE(apoE)-deficient(apoE-/-)mice.MethodsandResults-WedemonstratethatCD44isupregulatedandfunctionallyactivatedinaorticarchintheatherogenicenvironmentofapoE-/-micerelativeto...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期
  • EplerenoneWithValsartanEffectivelyReducesAtheroscleroticLesionbyAttenuationofOxidativeStressandInflammation

    【摘要】Objective-AngiotensinIIcontributestoatherogenesis,mainlythroughoxidativestressandinflammation.RecentdatasuggestthataldosteroneisimplicatedinsomeeffectsofangiotensinII.Wehypothesizedthataldosteronecoulddirectlycontributetooxidativestressandatheroscleroticlesionformation.MethodsandResults-...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第4期
  • HeritabilityofClotFormation,Morphology,andLysis

    【摘要】Objective—Therelativebalancebetweenclotformationandfibrinolysisisconsideredtoreflectthromboticpotentialfollowingvascularinjury.Theaimsofthepresentstudywereto(1)todeterminethecontributionofgeneticandenvironmentalfactorstovarianceinmeasuresofclotstructure/functionintheLeedsFamilyStud...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期
  • ConjugatedEquineEstrogen,EsterifiedEstrogen,ProthromboticVariants,andtheRiskofVenousThrombosisinPostmenopausalWomen

    【摘要】Background-Jointexposuretooralconjugatedequineestrogen(CEE)andprothromboticgeneticvariantsfactorIIG20210AorfactorVG1601A(Leiden)increasevenousthromboticrisk6-to16-foldinpostmenopausalwomen.Esterifiedestrogen(EE),analternativeestrogeniccompound,appearsnottobeassociatedwithincreasedriskand...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期
  • ElevatedSerumC-ReactiveProteinandFreeFattyAcidsAmongNondiabeticCarriersofMissenseMutationsintheGeneEncodingLaminA/C(LMNA)WithPartialLip

    AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective—Dunnigan-typefamilialpartiallipodystrophy(FPLD)duetomutantLMNAisamonogenicformofinsulinresistance.Affectedsubjects,especiallywomen,areatincreasedriskofearlycoronaryheartdisease(CHD).Althoughcommoninsulinresistanceisassociat...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第1期
  • 二、常近交系大鼠品系特征

    ...鼠白内障。可诱发常见的晶状体反射和持续性玻璃状体膜动脉的继发反应。收缩压低。  (十四)PVG系  1.形成:  ⑴起源:英国皇家科学院培育后引入Lister和Virol研究所,1946年被Glaxo引入并交繁殖。  ⑵近交代数:F70...

    参考资料医源资料库;医源图书馆;教材类;医用实验动物学
  • LifecourseSocioeconomicPosition,C-ReactiveProtein,andCarotidIntima-MediaThicknessinYoungAdults

    FromtheDepartmentofPsychology(M.K.,M.E.,L.K.-J.),UniversityofHelsinki,Finland;theDepartmentofSocialMedicine(D.A.L.,G.D.S.),UniversityofBristol,UK;theDepartmentsofMedicine(J.S.A.V.)andClinicalPhysiology(O.T.R.)andtheCardiovascularResearchUnit(M.J.),UniversityofTurku,Finland;andtheFinnishInstituteofOc...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第10期
  • DisparityofMCP-1mRNAandProteinExpressionsBetweentheCarotidArteryandtheAortainWHHLRabbits

    Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—ThisstudywasdesignedtoexaminewhyinWHHLrabbits,musculararteries,suchasthecarotidartery,arerelativelyresistanttoatherosclerosiscomparedwiththeaorta,withaspecialreferencetomonocytechemoattractantprotein(MCP)-1.Methodsand...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期
  • ProteolysisofthePericellularMatrix

    FromtheWihuriResearchInstitute,Helsinki,Finland.ABSTRACTThe2majorgeneralconceptsaboutthecellbiologyofatherogenesis,growthofsmoothmusclecells,andlipidaccumulationinmacrophages,ie,foamcellformation,havenotbeenabletosatisfactorilyexplainthegenesisofacutecoronarysyndromes.Rather,thebasicpathologybehindt...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第8期
  • AdiposeTissueandAtherosclerosis

    【摘要】Theprevalenceofobesity,especiallyamongtheyoung,isdramaticallyincreasingintheUnitedStates.Obesityisassociatedwithacceleratedatherosclerosisandincreasedratesofcardiovasculardeath.Therearemanyplausiblemechanismsbywhichanincreaseinadiposetissuecouldadverselyaffectthevesselwall.Theseincludeth...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第5期

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