【摘要】Objective-ToidentifyearlychangesinvasculargeneexpressionmediatedbyCD44thatpromoteatheroscleroticdiseaseinapolipoproteinE(apoE)-deficient(apoE-/-)mice.MethodsandResults-WedemonstratethatCD44isupregulatedandfunctionallyactivatedinaorticarchintheatherogenicenvironmentofapoE-/-micerelativeto...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期【摘要】Objective-AngiotensinIIcontributestoatherogenesis,mainlythroughoxidativestressandinflammation.RecentdatasuggestthataldosteroneisimplicatedinsomeeffectsofangiotensinII.Wehypothesizedthataldosteronecoulddirectlycontributetooxidativestressandatheroscleroticlesionformation.MethodsandResults-...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第4期【摘要】Objective—Therelativebalancebetweenclotformationandfibrinolysisisconsideredtoreflectthromboticpotentialfollowingvascularinjury.Theaimsofthepresentstudywereto(1)todeterminethecontributionofgeneticandenvironmentalfactorstovarianceinmeasuresofclotstructure/functionintheLeedsFamilyStud...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期【摘要】Background-Jointexposuretooralconjugatedequineestrogen(CEE)andprothromboticgeneticvariantsfactorIIG20210AorfactorVG1601A(Leiden)increasevenousthromboticrisk6-to16-foldinpostmenopausalwomen.Esterifiedestrogen(EE),analternativeestrogeniccompound,appearsnottobeassociatedwithincreasedriskand...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期AbstractTopAbstractIntroductionMethodsResultsDiscussionReferencesObjective—Dunnigan-typefamilialpartiallipodystrophy(FPLD)duetomutantLMNAisamonogenicformofinsulinresistance.Affectedsubjects,especiallywomen,areatincreasedriskofearlycoronaryheartdisease(CHD).Althoughcommoninsulinresistanceisassociat...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第1期...鼠白内障。可诱发常见的晶状体反射和持续性玻璃状体膜动脉的继发反应。收缩压低。 (十四)PVG系 1.形成: ⑴起源:英国皇家科学院培育后引入Lister和Virol研究所,1946年被Glaxo引入并交繁殖。 ⑵近交代数:F70...
参考资料医源资料库;医源图书馆;教材类;医用实验动物学FromtheDepartmentofPsychology(M.K.,M.E.,L.K.-J.),UniversityofHelsinki,Finland;theDepartmentofSocialMedicine(D.A.L.,G.D.S.),UniversityofBristol,UK;theDepartmentsofMedicine(J.S.A.V.)andClinicalPhysiology(O.T.R.)andtheCardiovascularResearchUnit(M.J.),UniversityofTurku,Finland;andtheFinnishInstituteofOc...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第10期Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—ThisstudywasdesignedtoexaminewhyinWHHLrabbits,musculararteries,suchasthecarotidartery,arerelativelyresistanttoatherosclerosiscomparedwiththeaorta,withaspecialreferencetomonocytechemoattractantprotein(MCP)-1.Methodsand...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期FromtheWihuriResearchInstitute,Helsinki,Finland.ABSTRACTThe2majorgeneralconceptsaboutthecellbiologyofatherogenesis,growthofsmoothmusclecells,andlipidaccumulationinmacrophages,ie,foamcellformation,havenotbeenabletosatisfactorilyexplainthegenesisofacutecoronarysyndromes.Rather,thebasicpathologybehindt...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第8期【摘要】Theprevalenceofobesity,especiallyamongtheyoung,isdramaticallyincreasingintheUnitedStates.Obesityisassociatedwithacceleratedatherosclerosisandincreasedratesofcardiovasculardeath.Therearemanyplausiblemechanismsbywhichanincreaseinadiposetissuecouldadverselyaffectthevesselwall.Theseincludeth...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第5期