...连续给药12周。1.4标本采集及制备1.4.1血清分别采取腹主动脉取血5~8ml/只,门静脉血1~2ml/只。室温静置4h内,用低速离心机3000rpm离心30min,取血清,分装,-70℃冰箱保存。1.4.2骨组织取左后肢股骨,剔除肌肉及筋膜,生理盐水冲...
参考资料医源资料库;在线期刊;中华现代中医学杂志;2007年第3卷第3期【摘要】Background-Aorticvalvecalcification(AVC)isconsidereddegenerative.Recentdatasuggestedlinkstoatherosclerosisorcoronarydisease(CAD).MethodsandResults-AVCandcoronaryarterycalcifications(CAC)wereprospectivelyassessedbyElectron-Beam-Computed-Tomographyin262population-basedresearchparticipants6...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第3期【摘要】Objective-Toidentifycommonvariationsingenesinthereversecholesteroltransportpathwaywithnongender-specificinfluenceonplasmalipidandapolipoproteinlevels.MethodsandResults-Anaverageof5singlenucleotidepolymorphisms(SNPs)weregenotypedwithineachof45genomicregions(54genes)inblacks(1131femalesand...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第8期...症有下肢深静脉血栓形成(DVT)、肺血栓栓塞(PTE)、伴动脉栓塞的无菌性血栓性心内膜炎(NBET)、脑栓塞、肝静脉栓塞、门静脉栓塞、慢性弥漫性血管内凝血、四肢和中枢性微血管动脉栓塞。也有以下肢静脉坏疽作为肺腺癌...
参考资料医源资料库;在线期刊;中华现代外科学杂志;2006年第3卷第4期FromtheDepartmentofClinicalBiochemistry(A.T.-H.,M.B.),Rigshospitalet,CopenhagenUniversityHospital,theDepartmentofCardiology(H.K.J.),SkejbyUniversityHospital,theDepartmentofMedicineB(R.S.),Hiller?dHospital,theTheCopenhagenCityHeartStudy(A.T.-H.,G.J.,B.G.N.),BispebjergUniversityHospital,andtheDepartme...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第1期【摘要】Objective-Granulocyte-macrophagecolony-stimulatingfactor(GM-CSF)isexpressedinatheroscleroticlesionsbutitssignificanceforlesiondevelopmentisunknown.Consequently,weinvestigatedthesignificanceofGM-CSFexpressionfordevelopmentofatheroscleroticlesionsinapolipoproteinE-deficient(apoE-/-)mice.Me...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第10期【摘要】Objective-Endothelialdysfunctionpredictsmorbidityandmortalityinpatientsatcardiovascularrisk.Endothelialfunctionmaybedecisivelyinfluencedbythedegreeofendothelialcellapoptosis.MethodsandResults-Totestthishypothesisinhumans,endothelial-dependentvasodilatationwasinvasivelyassessedin50patient...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第1期【摘要】Objective—Hypoxia-induciblefactor(HIF)-1istheregulatorysubunitofatranscriptionalcomplex,whichcontrolstherecruitmentofmultipotentprogenitorcellsandtissuerepairinischemictissuebyinducingstromalcell-derivedfactor(SDF)-1expression.BecauseHIF-1canbeactivatedundernormoxicconditionsinsmoo...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期FromtheDepartmentofMedicine,DivisionsofClinicalPharmacology(A.D.W.,J.P.G.,N.J.B.)andCardiovascularMedicine(F.A.,D.E.V.)andtheDepartmentofPathology(A.B.F.),VanderbiltUniversityMedicalCenter,Nashville,Tenn;CardiovascularandMetabolicDiseasesResearch(D.L.C.,H.E.),WyethResearch,Collegeville,Pa.Correspond...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第2期...高血压、脂代谢异常等代谢征的被纠正,将会有效的减少动脉粥样硬化和心脑血管疾病的发生率和死亡率。虽然本试验时间短,尚未看出糖尿病肾病、糖尿病视网膜病变和心脑血管疾病发生率的显著变化,如果能长期良好的控制...
参考资料合作平台;在线期刊;中华现代临床医学杂志;2005年第3卷第4期