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  • StatinTreatmentUpregulatesVascularNeuronalNitricOxideSynthaseThroughAkt/NF-BPathway

    【摘要】Objective-Three-hydroxy-3-methylglutarylcoenzymeA(HMG-CoA)reductaseinhibitors(statins)areknowntoenhancevascularexpressionofendothelial(eNOS)andinduciblenitricoxidesynthase(iNOS).Inthisstudy,weexaminedwhetherstatinsalsoupregulatevascularexpressionofneuronalNOS(nNOS).MethodsandResults-Incu...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期
  • WhatIstheMostAppropriateMethodologyforDetectionofConduitArteryEndothelialDysfunction?

    【摘要】Background-Useofupper-armarterialocclusiontoinducereactivehyperemia,andendothelium-dependentflow-mediateddilation(FMD)ofthebrachialartery,inducesgreaterconduitvesseldilatationthanlower-armocclusion.However,brachialarteryischemiaafterupperarmarterialocclusionmaymakethisapproachunreliable....

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第5期
  • MolecularDissectionofAngiotensinII-ActivatedHumanLOX-1Promoter

    【摘要】Objective-LOX-1,areceptorforoxidizedlow-densitylipoprotein,playsacriticalroleinatherosclerosis.Itsexpressionisupregulatedbypro-atherogenicstimuli,suchasangiotensinII(AngII).Inthisstudy,weexploredLOX-1transcriptionalpromoteractivationinresponsetoAngIIinhumancoronaryarteryendothelialcells(...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第5期
  • StereospecificandRedox-SensitiveIncreaseinMonocyteAdhesiontoEndothelialCellsbyHomocysteine

    【摘要】Objective-Previousstudieshaveshownthatelevatedhomocysteine(Hcy)levelspromotethedevelopmentofatheroscleroticlesionsinatherosclerosis-proneanimalmodels.ThereisevidencethatoxidantstresscontributestoHcy?sdeleteriouseffectsonthevasculature.Theaccumulationandadhesionofmonocytestothevascularend...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第3期
  • ContrastingEffectsofOralVersusTransdermalEstrogenonSerumAmyloidA(SAA)andHigh-DensityLipoprotein–SAAinPostmenopausalWomen

    FromtheDepartmentofInternalMedicine,UniversityofTexas,Dallas.ABSTRACTObjectives—PreviousstudiesindicatedthatoralestrogenincreasedC-reactiveproteinbyafirst-passhepaticeffect.Inthisstudy,wedeterminewhethertherouteofestrogenadministrationinfluencesserumamyloidA(SAA),anotheracute-phaseproteinproducedb...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期
  • PhysiologicalRolesofVascularNucleosideTransporters

    【摘要】Nucleosidetransporters(NTs)comprise2widelyexpressedfamilies,theequilibrativenucleosidetransporters(diffusion-limitedchannels)andconcentrativenucleosidetransporters(sodium-dependenttransporters).Becauseoftheiranatomicpositionattheblood-tissueinterface,vascularNTsareinanidealpositiontoinfl...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第5期
  • CellCycle–DependentRegulationofSmoothMuscleCellActivation

    FromCardiothoracicSurgery(M.J.M.),UniversityofCalifornia,SanFranciscoMedicalSchool,SanFrancisco,Calif;CardiovascularResearch(V.J.D.),BrighamandWomen’sHospital/HarvardMedicalSchool,Boston,Mass;theDepartmentofInternalMedicineII/Cardiology(R.C.B.-D.),DresdenUniversityofTechnology,Dresden,Germany;theD...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第5期
  • 重症急性胰腺炎大鼠TNF-α和ICAM-1的表达及其意义

    ...l/kg体重。1.2.2标本采制和检测制模后10h,两组大鼠经腹主动脉采血,血液4℃过夜,3000rpm4℃离心15min后取血清,-20℃保存。肝功能检查测谷丙转氨酶(ALT),肾功能检查测肌酐(CRE)。ALT、CRE、TNF-α以及淀粉酶的测定均按试...

    参考资料医源资料库;在线期刊;中华医学实践杂志;2008年第7卷第1期
  • EGF-LikeDomainofTenascin-CIsProapoptoticforCulturedSmoothMuscleCells

    FromtheAtherosclerosisResearchCenter(K.W.,C.L.,P.K.S.,K-J.W.,B.G.S.),DivisionofCardiology,andBurnsandAllenResearchInstitute,Cedars-SinaiMedicalCenter,andUCLASchoolofMedicine,LosAngeles,Calif;andtheDepartmentofPathology(S.M.S.),UniversityofWashington,Seattle.ABSTRACTObjective—Basedonourpreviousobse...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第8期
  • AsynchronousShearStressandCircumferentialStrainReducesEndothelialNOSynthaseandCyclooxygenase-2butInducesEndothelin-1GeneExpressioninEndothel

    FromtheBiomolecularTransportDynamicsLaboratory,DepartmentofBioengineering(M.B.D.,D.E.B.)andCenterforMolecularToxicologyandCarcinogenesis(J.P.V.)atThePennsylvaniaStateUniversity,FenskeLab,UniversityPark;andDepartmentofBiomedicalEngineering(J.M.T.),CityCollegeofNewYork/CUNY,NewYork.ABSTRACTObjective...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第11期

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