...动静脉支紧贴盆壁而行并相互吻合成环。盆腔脏器有伴其动脉的静脉支和异常丰富的静脉丛（图3.5.12.1-0-8，3.5.12.1-0-9）。后者又多围绕盆腔内壁，且相互通连。骨盆骨折时易使邻近的血管损伤而引起大出血，除形成盆腔血肿外，...
词条骨科手术；下肢骨折切开复位及内固定；骨盆骨折的手术治疗；手术【摘要】Objective-Arterialcalcificationhasbeenassociatedwithmatrixmetalloproteinase(MMP)-mediatedelastindegradation.Inthisstudy,weinvestigatedwhetherinhibitingMMPactivitycouldreducecalciumaccumulationinrodentmodelsofaorticcalcification.MethodsandResults-AorticcalcificationwasfirstinducedinmaleSp...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期【摘要】Niemann-PickC1-like1protein(NPC1L1)wasrecentlyshowntobethemoleculartargetofthecholesterolabsorptioninhibitorclassofdrugs,ofwhichezetimibeisthefirstwidelyusedmember.Sinceitsdiscovery,NPC1L1hasalsobeenshowntoplayafocalphysiologicalroleinintestinalabsorptionofsterols,includingplantsterolsan...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第11期FromtheDepartmentofVascularBiologyandThrombosisResearch(A.F.,V.N.B.,G.K.,A.K.,B.R.B.,N.L.),UniversityofVienna,Austria;WilheminenHospital(A.F.),Vienna,Austria;theDepartmentofCardiovascularMolecularBiology(A.S.,C.W.),UniversityofAachen,Germany;andtheCardiologyResearchCenter(P.B.),Moscow,Russia.Corresp...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第3期【摘要】Objective-Antimicrobialpeptidesareeffectormoleculesoftheinnateimmunesystem.Tounderstandthefunctionofvascularinnateimmunityinatherosclerosis,weinvestigatedtheroleofLL-37,acathelicidinantimicrobialpeptide,inthediseaseprocess.MethodsandResults-Usingreal-timepolymerasechainreaction,wefounda6...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第7期...IFN-α1b2000万u×6个月；肢体非淋巴结转移可辅以氮烯咪胺动脉灌注5943III期不能切除、IV参考ⅡB期切除易手术之肿瘤，IFN-α1b、塞来昔布治疗参照Ⅲ期，若有效，持续至肿瘤消失后1年；基因检测阳性可选相应的靶向药物；可试用化...
词条临床路径；2016年版临床路径【摘要】Objective-Clinicalstudiesdemonstratethatmineralocorticoidreceptor(MR)antagonismimprovesoutcomesincardiovascularpatientsandthatvascularcalcificationcorrelateswithadversecardiacevents.Wehaverecentlydemonstratedthathumanvascularsmoothmusclecells(VSMCs)expressfunctionalMRsthat,inresponsetoal...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第4期【摘要】Objective—Hypoxiainduciblefactor(HIF)playsapivotalroleintheadaptationtoischemicconditions.Itsactivityismodulatedbyanoxygen-dependenthydroxylationofprolineresiduesbyprolylhydroxylases(PHD).MethodsandResults—Wediscovered2uniquecompounds(TM6008andTM6089),whichinhibitedPHDandstab...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第12期Abstract：TopAbstractIntroductionMethodsResultsDiscussionReferences：Objective—ApolipoproteinE(apoE)mediatescellularcholesteroleffluxandplaysacrucialroleintheinhibitionofatherogenesis.Weinvestigatedwhetherthereisanisoform-specificdifferenceinitsfunctionforcholesteroleffluxfromcholesterol-loadedR...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2003年第23卷第2期...道平滑肌松弛作用，此外尚有增强心肌收缩力，舒张冠状动脉外周血管和胆管；增加肾血流量，提高肾小球滤过率，减少肾小管对钠和水的重吸收，而发挥平喘、利尿作用。茶碱口服吸收不完全，生物利用度的个体间差异较大，...
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