FromtheDepartmentofPediatrics,UniversityofWashington,Seattle,Wash.ABSTRACTObjective—Increasedexpressionofhumanhepaticlipase(HL)oracatalyticallyinactive(ci)HLclearsplasmacholesterolinmicedeficientinlow-densitylipoproteinreceptors(LDLr)andmurineHL.WehypothesizedthatincreasedexpressionofbothHLandciHL...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第9期【摘要】Background-Obesityisgenerallyacceptedasariskfactorforprematureatherosclerosis.SubclinicalinflammationasquantifiedbybloodlevelsofC-reactiveprotein(CRP)contributestothedevelopmentandprogressionofatherosclerosis.Wehypothesizedthatinflammationinobesechildrenisrelatedtofunctionalandearlymorph...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第11期【摘要】Objective-TheuseoftheHIVproteaseinhibitorritonavir(RTV)isfrequentlyassociatedwithhypertriglyceridemiaandlipodystrophy.Theaimofourstudywastodeterminethemechanismunderlyingtheobservedhypertriglyceridemia.MethodsandResults-FeedingfemaleAPOE*3-LeidentransgenicmiceaWestern-typedietsupplemente...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第1期FromtheDepartmentsofSurgery(V.M.M.),PhysiologyandBioengineering(V.M.M.),Urology(D.J.T.),andInternalMedicine,DivisionofEndocrinology(P.Y.L.),MayoClinicCollegeofMedicine,Rochester,MN.Incidenceofcardiovasculardiseaseisconsistentlygreaterinmenthaninwomenduringthefirstfivedecadesoflife.1Becausethisgender...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第6期FromtheDepartmentsofMedicine(R.P.C.,J.X.R.,E.T.,V.I.E.,H.M.D.,J.T.F.,E.A.F.),MarcandRutiBellPrograminVascularBiologyintheLeonH.CharneyDivisionofCardiology,andCellBiology,NewYorkUniversitySchoolofMedicineandDepartmentofMedicineandTheZenaandMichaelA.WienerCardiovascularInstitute,MountSinaiSchoolofMedi...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第10期...维化组大鼠（此时剩12只大鼠，其余造模过程中死亡）股动脉放血处死（处死前称体重），留取血液及全部肝脏:称肝脏湿重，每只大鼠取相同部位肝脏用4%中性甲醛固定，剩余-80℃低温冰箱保存;血液1500rpm离心10min后将血清置于-80...
参考资料合作平台；在线期刊；中华中西医杂志；2004年第5卷第17期；论著【摘要】Lipoproteinlipase(LPL)hydrolyzestriglyceridesinthecirculationandpromotesthehepaticuptakeofremnantlipoproteins.Sincethegenewasclonedin1989,morethan100LPLgenemutationshavebeenidentified,themajorityofwhichcauselossofenzymaticfunction.Incontrasttothis,thenaturallyoccurringLPLS447Xvariantisas...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第6期FromtheDepartmentsofMedicine,Microbiology,Immunology,andMolecularGenetics,andHumanGenetics(X.Wang,P.G.,J.W.,X.Wu,H.Q.,P.W.,L.W.C.,A.J.L.),UniversityofCalifornia,LosAngeles;theDivisionofBiology(J.L.G.),CaliforniaInstituteofTechnology,Pasadena;andtheDepartmentofCardiovascularMolecularSciencesandTechno...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第10期FromtheLipidMetabolismLaboratory(B.F.A.,K.V.H.,E.J.S.),HNRCAatTuftsUniversity,Boston,Mass;DepartmentofVeteransAffairs(D.C.),WestHaven,Conn;DepartmentofBiostatistics(L.A.C.,S.D.),BostonUniversity,Massachusetts;CenterforChronicDiseaseOutcomesResearch(H.E.B.),VeteransAffairsMedicalCenter,Minneapolis,Mi...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第10期FromtheCardiovascularResearchInstitute(R.J.H.,R.L.H.)andtheDepartmentofAnatomy(R.L.H.),UniversityofCaliforniaSanFrancisco,CA.CorrespondencetoRichardJ.Havel,CardiovascularResearchInstitute,UniversityofCaliforniaSanFrancisco,SanFrancisco,CA94943-0130.E-mailhavelr@itsa.ucsf.eduBrownandGoldsteindescribe...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第2期