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  • ElevatedMarkersofEndothelialDysfunctionPredictType2DiabetesMellitusinMiddle-AgedMenandWomenFromtheGeneralPopulation

    【摘要】Objective-UsingtheMonitoringofTrendsandDeterminantsinCardiovascularDisease(MONICA)/CooperativeResearchintheRegionofAugsburg(KORA)database,weinvestigatedprospectivelywhetherincreasedlevelsofsolubleE-selectin(sE-selectin),solubleintercellularadhesionmolecule1(sICAM-1),andvonWillebrandfacto...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第2期
  • DysregulatedBoneMorphogeneticProteinSignalinginMonocrotaline-InducedPulmonaryArterialHypertension

    【摘要】Background-Mutationsinthebmpr2gene,encodingthetypeIIbonemorphogeneticprotein(BMP)receptor,havebeenidentifiedinpatientswithpulmonaryarterialhypertension(PAH),implicatingBMPsignalinginPAH.TheaimofthisstudywastoassessBMPsignalinganditsphysiologicaleffectsinamonocrotaline(MCT)modelofPAH.Meth...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第5期
  • ANaturalAntibodytoOxidizedCardiolipinBindstoOxidizedLow-DensityLipoprotein,ApoptoticCells,andAtheroscleroticLesions

    【摘要】Objective-Cardiolipin(CL)isfoundinmembranesofbacteria,intheinnermembraneofmitochondriaandinplasmalow-densitylipoprotein(LDL).Anticardiolipinantibodies(aCL)areassociatedwithdiseasestates,andwehavesuggestedthatmanyaCLbindtooxidizedCL(oxCL)butnotnativeCL.Todeterminetheimmunogenicityandorigi...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第9期
  • 乌梅丸

    ...很强的解热降温作用以及镇静、镇痛作用,其镇痛强度与氨基比林0.5g/kg相当;细辛具有ACTH样作用,能增强肾上腺皮质功能。黄连能抑制中枢发热介质的生成与释放,具有显著的解热作用;黄连所含叔胺类生物碱能透过血脑屏障...

    词条中成药;消化系统药物;消化系统中成药;药物;中医学;中药学;方剂学;方剂
  • Nrf2GeneTransferInducesAntioxidantEnzymesandSuppressesSmoothMuscleCellGrowthInVitroandReducesOxidativeStressinRabbitAortaInVivo

    【摘要】Background-Reactiveoxygenspecies(ROS)playamajorroleinvascularinflammationandpathophysiologyofmanyvasculardiseasessuchasatherosclerosisandinjury-inducedneointimaformationafterballoonangioplasty.NuclearfactorE2-relatedfactor-2(Nrf2)isatranscriptionfactororchestratingantioxidantandcytoprote...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第4期
  • EndotoxinInducesToll-LikeReceptor4ExpressioninVascularSmoothMuscleCellsviaNADPHOxidaseActivationandMitogen-ActivatedProteinKinaseSignaling

    【摘要】Objective-Toll-likereceptor4(TLR4)playsamajorrolemediatingendotoxin-inducedcellularinflammationandregulatesvascularsmoothmusclecell(VSMC)proliferation,whichisrelatedtoatherogenesisandrestenosis.Thisstudywasconductedtoinvestigatethemechanismsinvolvedinlipopolysaccharide(LPS)-inducedTLR4ex...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第12期
  • InVivoActionsofAngiopoietinsonQuiescentandRemodelingBloodandLymphaticVesselsinMouseAirwaysandSkin

    【摘要】Objective-Weinvestigatedandcomparedtheinvivoeffectsofallfourangiopoietins(COMP-Ang1,Ang2,Ang3,andAng4)onbloodandlymphaticvascularremodelinginadultmice.Weanalyzedthemicrovasculatureoftracheaandearskin,andcomparedquiescentskinmicrovasculaturewiththatduringwoundhealing.MethodsandResults-Wew...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第3期
  • MultipleEffectsofHighMobilityGroupBoxProtein1inSkeletalMuscleRegeneration

    【摘要】Objective—Highmobilitygroupbox1protein(HMGB1)isacytokinereleasedbynecroticandinflammatorycellsinresponsetoinjury.WeexaminedtheroleofHMGB1inskeletalmuscleregenerationafterhindlimbischemia.MethodsandResults—Unilateralhindlimbischemiawasinducedinmicebyfemoralarterydissection.HMG...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第11期
  • CarvedilolInhibitsTumorNecrosisFactor-–InducedEndothelialTranscriptionFactorActivation,AdhesionMoleculeExpression,andAdhesivenesstoHumanMononu

    FromtheNationalYang-MingUniversitySchoolofMedicine(J.-W.C.,Y.-H.C.,T.-C.W.,Y.-L.C.,S.-J.L.),CardiovascularResearchCenter;theDivisionofCardiology(J.-W.C.,T.-C.W.,S.-J.L.),DepartmentofMedicine,TaipeiVeteransGeneralHospital;andtheGraduateInstituteofMedicalScience(F.-Y.L.),NationalDefenseMedicalCenter,T...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第11期
  • DifferentialRegulationofHomocysteineTransportinVascularEndothelialandSmoothMuscleCells

    【摘要】Objective—Wepreviouslyreportedthathomocysteine(Hcy)inhibitsendothelialcell(EC)growthandpromotesvascularsmoothmusclecell(VSMC)proliferation.ThisstudycharacterizedanddirectlycomparedHcytransportinculturedhumanaorticECs(HAECs)andsmoothmusclecells(HASMCs).MethodsandResults—Hcy(10...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第9期

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