...骨变薄，负重部位软骨破裂，缺损，继之软骨下骨质外露硬化，关节边缘区软骨骨化形成骨赘，日后可因跌打扭伤，关节囊、滑膜及邻近滑囊壁才出现炎症肥厚，产生关节积液。关节囊和滑膜可发生软骨化生和骨化。剥脱的软骨...
参考资料医源资料库；在线期刊；中华现代影像学杂志；2007年第4卷第9期Abstract：TopAbstractIntroductionMethodsResultsDiscussionReferences：Objective—Phosphatidylcholinehydroxyalkenals(PC-HAs)areaclassofoxidizedPCsderivedfromlipidperoxidationofarachidonateorlinoleateatthesn-2positiontoformterminal-hydroxy,-,andß-unsaturatedaldehydes.Theaimofthisstudywastochar...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2003年第23卷第2期【摘要】Objective-Pleiotrophin(PTN)isacytokinethatisexpressedbymonocytes/macrophagesinischemictissuesandthatpromotesneovascularization,presumablybystimulatingproliferationoflocalendothelialcells.However,theeffectofPTNonmonocytes/macrophagesremainsunknown.WeinvestigatedtheroleofPTNinregulatingthe...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第6期【摘要】Objective-Althoughthemetabolicsyndrome(MS)isassociatedwithincreasedcardiovascularrisk,itsrelationshipwithatheroscleroticprogressionislesswelldefined.WesoughttodeterminewhethertheMSpredictsangiographicprogressionofcoronaryheartdiseaseinacohortofpostmenopausalwomen.MethodsandResults-Atotal...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第1期SharonC.Tai;G.BrettRobb;PhilipA.MarsdenFromtheRenalDivisionandDepartmentofMedicine,St.Michael’sHospitalandUniversityofToronto,Ontario,Canada.CorrespondencetoPhilipA.Marsden,Room7358,MedicalSciencesBuilding,UniversityofToronto,1KingsCollegeCircle,Toronto,OntarioM5S1A8Canada.E-mailp.marsden@utoronto...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第3期【摘要】Objective-Recentstudieshaveprovidedstrongevidenceforthepresenceofozoneinatheroscleroticlesions.Inaddition,modificationofLDLhasbeensuggestedtobeinvolvedinatherosclerosis.InthepresentstudywewantedtoinvestigatewhetherLDLexposedtoozone(ozLDL)isabletomodulatetheNF-Bsystem,asaparadigmforinflam...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第1期【摘要】Background—Peripheralarterydisease(PAD)isaprevalentcardiovasculardisorderthatresultsintissueischemiawhichcanprogresstocriticallimbischemia.RestorationoftissueperfusioninthesettingofchronicischemiathroughstimulationofarteriogenesisandangiogenesisremainsakeytherapeutictargetforPAD.Ho...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第9期FromClinicaMedica(C.G.,G.G.,M.F.,G.M.),UniversityofMilano-BicoccaandSanGerardoHospital,Monza;DipartimentoScienzeFarmacologiche(A.Z.,F.M.M.,A.C.),CentroStudiAterosclerosi,UniversityofMilano;CentroInteruniversitariodiFisiologiaClinicaeIpertensione(G.M.),Milano-Bicocca,MilanoePavia;OspedaleMaggioreMila...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第2期【摘要】Smokingcausesupto11%oftotalglobalcardiovasculardeaths.Smokinghasnumerouseffectsthatmaypromoteatherosclerosisthroughvascularinflammationandoxidativestress,butthepathogenesisofsmoking-relatedcardiovasculardiseaseremainsincompletelyunderstood.Thematrixmetalloproteinases,afamilyofendopeptida...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第2期【摘要】Objective-Thedevelopmentofamurinemodelofatheroscleroticplaquerupture.MethodsandResults-TheleftcommoncarotidarteriesofmaleapolipoproteinE(apoE)-deficientmice(9weeksold)wereligatedjustproximaltotheirbifurcations.After4weeksonastandarddiet,themicereceivedpolyethylenecuffplacementjustproxima...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第6期