【摘要】Objective-Todeterminethesignificanceoffibroblastgrowthfactorreceptor(FGFR)expressionforthedevelopmentofatheroscleroticlesionsinapoE-deficient(apoE-/-)mice.MethodsandResults-ApoE-/-micefedahigh-fatdietwereadministeredtheFGFRtyrosinekinaseinhibitorSU5402(25mg/kg/dsc),whichinhibitedneointim...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第8期【摘要】Objective-Impairedflow-mediateddilation(FMD)occursindiseasestatesassociatedwithatherosclerosis,includingSLE.TheprimaryhemodynamicdeterminantofFMDiswallshearstress,whichiscriticallydependentontheforearmmicrocirculation.WeexploredtherelationshipbetweenFMD,diastolicshearstress(DSS),andthefo...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第10期【摘要】Objective-Theregulationofendothelialcelladhesionmolecules(CAMs)byvascularendothelialgrowthfactor(VEGF)wasinvestigatedincellculturesandinarabbitmodelofatherogenicneointimaformation.MethodsandResults-VEGFregulationofvascularCAM-1(vascularcelladhesionmolecule),intercellularCAM-1(intercellul...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第3期【摘要】Objective-Toevaluatetheroleoffactor(F)VIIIinchildrenwithnon-cancerrelatedvenousthrombosis(DVT),post-thromboticsyndrome(PTS)orrecurrentDVT.MethodsandResults-FVIIIlevelsweremeasuredinWhitepatientsandage-andgender-matchedhealthycontrols.HeritabilityoffactorVIIIwasestimatedin99pedigreesbythe...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第8期【摘要】Objective-TherelationshipbetweenChlamydiapneumoniae(Cpn)infectionandarterialmeasuresofpreclinicalatherosclerosishasremainedcontroversial.Becauseatherogenesisbeginsinearlylife,weexaminedwhethercarotidandaorticintima-mediathickness(IMT)andbrachialarteryendothelialfunctionareassociatedwithC...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第3期【摘要】Objectives-Atherosclerosismaybecausedbyincreasedendothelialdamageandbyaconsumptivelossofendothelialrepaircapacitybyendothelialprogenitors.Arterialstiffnessisareliablemarkerofatherosclerosisandapositivecorrelateofendothelialdamage.WeinvestigatedwhetheranincreasedratioofCD31+/CD42-micropar...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第11期【摘要】Objective—ThepurposeofthisstudywastoexaminetheeffectsofPPAR-agonistrosiglitazone,relativetosulfonylureas,oncirculatinglevelsofadiponectinandtheprothromboticfactor,plasminogenactivatorinhibitor(PAI)-1,intype2diabeticpatients,andtoinvestigate,inanimalmodels,whethertheantithromboticac...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期FromtheDepartmentofCardiovascularMedicine(Y.M.,H.S.,T.U.,K.A.,K.O.,T.H.K.M.,Y.E.,Y.F.,A.T.),theDepartmentofBiomedicalEngineering(T.M.),andtheDepartmentofDevelopmentalMolecularAnatomy(K.N.,Y.S.),KyushuUniversityGraduateSchoolofMedicalSciences,Fukuoka,Japan.CorrespondencetoHiroakiShimokawa,MD,PhD,Depa...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期FromtheDepartmentofExperimentalImmunohaematology(P.d.C.M.,N.v.d.B.,P.L.H.,J.J.Z.),SanquinResearch,Amsterdam,TheNetherlands;DepartmentofPulmonaryDiseases(L.H.U.,L.K.),UniversityHospitalUtrecht,Utrecht,TheNetherlands;DepartmentofHematology(J.J.Z.),AcademicalMedicalCenter,Amsterdam,TheNetherlands.Corre...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期【摘要】Objective-Endothelialdysfunctionandvasculardysregulationcontributetothepathologicaleffectsofradiationontissues.Theobjectivesofthisstudyweretoassesstheacuteeffectofirradiationonacetylcholine(Ach)-induceddilationofgutsubmucosalmicrovessels.MethodsandResults-Ratswereexposedinvivoto1to9cGyin...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第2期