FromtheDepartmentofCardiologyandPulmonaryMedicine(K.S.,M.H.,C.G.,M.P.,S.K.),UniversityofGoettingen,Goettingen,Germany,andtheDepartmentofCellBiology(C.D.,D.J.L.),DivisionofVascularBiology,TheScrippsResearchInstitute,LaJolla,Calif.CorrespondencetoStavrosKonstantinides,MD,DepartmentofCardiologyandPulmo...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期【摘要】Objective-ActivatedfactorXIII(FXIII)crosslinksfibrintoenhancethemechanicalstrengthofabloodclotandincreaseitsresistancetofibrinolysis.TheprevalenceofacommonvariantintheFXIII-Agene(V34L)hasbeenreportedtobelowerinpatientswithmyocardialinfarctionandischemicstrokethanincontrols,suggestingapro...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第8期【摘要】Objective-Todemonstrate,quantify,andmechanisticallydissectantiatheroscleroticeffectsoffenofibratebesidesloweringplasmacholesterolperse.MethodsandResults-ApoE*3Leidentransgenicmicereceivedeitherahigh-cholesteroldiet(HC)orHCcontainingfenofibrate(HC+FF)resultingin52%plasmacholesterol-loweri...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第10期FromtheMolecularDiseaseBranch,NationalHeart,Lung,andBloodInstitute(NHLBI),NationalInstitutesofHealth(NIH),Bethesda,Md.ABSTRACTTheroleofhepaticlipaseasamultifunctionalproteinthatmodulateslipoproteinmetabolismandatherosclerosishasbeenextensivelydocumentedoverthelastdecade.Hepaticlipasefunctionsasalipo...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第10期...情况下,在胃和十二指肠产生的急性溃疡。由于老年人中动脉硬化的广泛存在,其心、脑血管急性事件的发生率明显高于其他人群,而且老年人随机体免疫力的下降易导致重症感染,使临床上老年人并发应激性溃疡的机会也明显...
词条疾病;消化内科【摘要】Objective—Toinvestigatetheassociationof-glutamyltransferase(GGT)withincidentCHDandstroke.GGTisamarkerofalcoholintakebutmayalsoreflectoxidativestressandnonalcoholicfattyliverdisease.Alanineaminotransferase(ALT)istheenzymemostcloselyassociatedwithliverfatcontent.MethodsandResults&mda...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第12期FromtheW.K.WarrenMedicalResearchInstitute,DepartmentofMedicine,UniversityofOklahomaHealthSciencesCenter,OklahomaCity.CorrespondencetoGeorgeL.Dale,PhD,DepartmentofMedicine;BSEB-330,OUHealthSciencesCenter,941StantonYoungBlvd,OklahomaCity,OK73104.E-mailgeorge-dale@ouhsc.eduAbstractObjective—Coated-pl...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第2期【摘要】Thrombosisoccursinadynamicrheologicalfieldthatconstantlychangesasthethrombusgrowstoocclusivedimensions.Intheinitiationofthrombosis,flowconditionsnearthevesselwallregulatehowquicklyreactivecomponentsaredeliveredtotheinjuredsiteandhowrapidlythereactionproductsaredisseminated.Whereasthedeli...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第8期FromTheHeartResearchInstitute,Sydney,Australia.ABSTRACTObjective—Theinvolvementoftransitionmetalsinatherosclerosisiscontroversial.Someepidemiologicalstudieshavereportedarelationshipbetweeniron(Fe)andcardiovasculardisease,whereasothershavenot.Experimentalstudieshavereportedelevatedlevelsofironandco...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第5期【摘要】Objective-Alowlevelofplasmahigh-densitylipoproteincholesterol(HDL-C)isamajorriskfactorforcoronaryatherosclerosis.ToidentifynovelgenesregulatingplasmaHDL-Clevels,weinvestigated13multigenerationalFrenchCanadianfamilieswithanaverageof12affectedindividualsperfamilyforgenome-widesignals,which...
参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第2期