【摘要】Objective—Residentimmunecellsareahallmarkofatheroscleroticlesions.ThesphingolipidanaloguedrugFTY720mediatesretraffickingofimmunecellsandinhibitstheirhomingtoinflammatorysites.WehaveevaluatedtheeffectofFTY720onatherogenesisandlipidmetabolism.MethodsandResults—ApoE–/&ndas...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第11期【摘要】Objective-Wetestedthehypothesisthathyperhomocysteinemiaandhypercholesterolemiapromotearterialthrombosisinmice.MethodsandResults-MaleapolipoproteinE(Apoe)-deficientmicewerefedoneoffourdiets:control,hyperhomocysteinemic(HH),highfat(HF),orhighfat/hyperhomocysteinemic(HF/HH).Totalcholesterol...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2007年第27卷第1期Abstract：TopAbstractIntroductionMethodsResultsDiscussionReferences：Objective—Weconductedawhole-genome,multipointlinkagescreentolocalizeapreviouslyreportedmajorlocusaccountingfor56%to67%oftheadditivegeneticeffectsoncovariate-adjustedplasmaHDLcholesterol(HDL-C)levelsinMexicanAmericansfromtheSanA...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2003年第23卷第2期FromtheDivisionofVascularSurgery(E.S.,M.S.,R.L.D.),StanfordUniversity,andSurgicalService,VeteransAffairsPaloAltoHealthCareSystem,PaloAlto,Calif;andtheSecondDepartmentofPathology(H.N.,K.K.,H.M.),AkitaUniversitySchoolofMedicine,Akita,Japan.ABSTRACTObjectives—Bonemarrow-derivedvascularprogenitorcells...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2004年第24卷第10期【摘要】Thedietaryrecommendationsmadeforcarbohydrateintakebymanyorganizations/agencieshavechangedovertime.Earlyrecommendationswerebasedontheneedtoensuredietarysufficiencyandfocusedonmeetingmicronutrientintakerequirements.Becausecarbohydrate-containingfoodsarearichsourceofmicronutrients,starches,...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第9期【摘要】Objective-Interventionsthatpromoteliver-directedcholesterolfluxcansuppressatherosclerosis,asdemonstratedforscavengerreceptor-BIoverexpressioninhypercholesterolemicmice.Inanalogy,wespeculatethatincreasinglipoproteinfluxtotheliverviatheasialoglycoproteinreceptor(ASGPr)maybeoftherapeuticval...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第1期【摘要】Objective-Duringatherogenesis,macrophagesmigrateintothesubendothelialspacewheretheyingestdepositedlipoproteins,accumulatelipids,andtransformintofoamcells.Itisunclearwhythesemacrophagesdonotremovetheirlipidloadsfromtheregion.Thisstudywasaimedattestingthehypothesisthatmacrophagebehaviorisa...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第2期【摘要】Objective-Granulocyte-macrophagecolony-stimulatingfactor(GM-CSF)isexpressedinatheroscleroticlesionsbutitssignificanceforlesiondevelopmentisunknown.Consequently,weinvestigatedthesignificanceofGM-CSFexpressionfordevelopmentofatheroscleroticlesionsinapolipoproteinE-deficient(apoE-/-)mice.Me...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第10期FromINSERMU-466andBiochimieIFR-31(F.R.,N.A.,C.V.,A.-V.C.,A.N.-S.,R.S.),FacultyofMedicine,UniversityPaulSabatier,Toulouse,France;INSERMU-563(R.B.),CentredePhysiopathologiedeToulouse-Purpan,DepartmentLipoproteinesetMediateursLipidiques,IFR-30,Toulouse,France.CorrespondencetoR.SalvayreorA.Negre-Salvayr...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2005年第25卷第6期【摘要】Objective-SR-BI/apolipoprotein(apo)Edoubleknockout(dKO)miceexhibitmanyfeaturesofhumancoronaryheartdisease(CHD),includingocclusivecoronaryatherosclerosis,cardiachypertrophy,myocardialinfarctions,andprematuredeath.Herewedeterminedtheeffectsonthispathologyofhepaticlipase(HL)deficiency,which...
参考资料医源资料库；在线期刊；动脉硬化血栓血管生物学杂志；2006年第26卷第3期