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  • MatrixManagement

    FromAstraZeneca(C.W.,W.M.,E.H.-C.),RD,MolecularPharmacology,M?lndal;andWallenbergLaboratory(E.H.-C.),GothenburgUniversity,SahlgrenskaAcademy,Sweden.CorrespondencetoDrEvaHurt-Camejo,MolecularPharmacology,RACVGI,AstraZeneca,RD,M?lndal,Sweden,S-43183.E-maileva.hurt-camejo@astrazeneca.comGeometricremode...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第1期
  • MinimallyOxidizedLDLOffsetstheApoptoticEffectsofExtensivelyOxidizedLDLandFreeCholesterolinMacrophages

    【摘要】Objective-Lipid-loadedmacrophage-derivedfoamcellspopulateatheroscleroticlesionsandproducemanypro-inflammatoryandplaque-destabilizingfactors.Anexcessiveaccumulationofextensivelyoxidizedlow-densitylipoprotein(OxLDL)orfreecholesterol(FC),bothofwhicharebelievedtobemajorlipidcomponentsofmacro...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第5期
  • DirectDetectionandQuantificationofTransitionMetalIonsinHumanAtheroscleroticPlaques:EvidenceforthePresenceofElevatedLevelsofIronandCopper

    FromTheHeartResearchInstitute,Sydney,Australia.ABSTRACTObjective—Theinvolvementoftransitionmetalsinatherosclerosisiscontroversial.Someepidemiologicalstudieshavereportedarelationshipbetweeniron(Fe)andcardiovasculardisease,whereasothershavenot.Experimentalstudieshavereportedelevatedlevelsofironandco...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第5期
  • 肝纤维化

    ...是慢性病毒性肝炎的临床及病理演变来看,肝纤维化和肝硬化是连续的发展过程,二者难以截然分开。【治疗措施】抗纤维化的治疗旨在减轻纤维化的程度、延缓其发展,乃至逆转其病理进程。为此抗纤维化的治疗应包括:①针...

    参考资料求医问药;疾病手册;消化内科
  • 肝纤维化

    ...是慢性病毒性肝炎的临床及病理演变来看,肝纤维化和肝硬化是连续的发展过程,二者难以截然分开。治疗措施:抗纤维化的治疗旨在减轻纤维化的程度、延缓其发展,乃至逆转其病理进程。为此抗纤维化的治疗应包括:①针对...

    词条疾病
  • OfMice,Men,andHormones

    FromtheDepartmentsofSurgery(V.M.M.),PhysiologyandBioengineering(V.M.M.),Urology(D.J.T.),andInternalMedicine,DivisionofEndocrinology(P.Y.L.),MayoClinicCollegeofMedicine,Rochester,MN.Incidenceofcardiovasculardiseaseisconsistentlygreaterinmenthaninwomenduringthefirstfivedecadesoflife.1Becausethisgender...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2004年第24卷第6期
  • Macrophage-ExpressedGroupIIASecretoryPhospholipaseA2IncreasesAtheroscleroticLesionFormationinLDLReceptor–DeficientMice

    Abstract:TopAbstractIntroductionMethodsResultsDiscussionReferences:Objective—TransgenicmiceexpressinghumangroupIIAsecretoryphospholipaseA2(groupIIAsPLA2)spontaneouslydevelopatheroscleroticlesions.Themechanismforthisproatherogeniceffectislikelymultifactorial,becauseHDL-cholesterolissignificantl...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2003年第23卷第2期
  • LowCirculatingEndogenousSecretoryReceptorforAGEsPredictsCardiovascularMortalityinPatientsWithEnd-StageRenalDisease

    【摘要】Objective-Receptorforadvancedglycationend-products(RAGE)isinvolvedindiabeticvascularcomplications.WehaverecentlyshownthatplasmaendogenouslysecretoryRAGE(esRAGE),analternativelysplicedformofRAGE,iscloselyassociatedwithmetabolicsyndromeandatherosclerosis.Here,weevaluatedifplasmaesRAGEisapr...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2007年第27卷第1期
  • ClopidogrelImprovesSystemicEndothelialNitricOxideBioavailabilityinPatientsWithCoronaryArteryDisease

    【摘要】Background-Plateletstimulationandactivationareknownnotonlyasprerequisiteofclotformationbutareincreasinglyrecognizedasimportantcontributorstoinflammationandvascularinjury.Thepresentstudyinpatientswithsymptomaticcoronarydiseaseinvestigatedwhetherplateletadenosinediphosphatereceptorblockade...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2006年第26卷第7期
  • ExerciseandtheProthromboticState

    FromtheHaemostasis,Thrombosis,andVascularBiologyUnit,UniversityDepartmentofMedicine,CityHospital,BirminghamB187QH,England.CorrespondencetoProfessorG.Y.H.Lip,UniversityDepartmentofMedicine,CityHospital,BirminghamB187QH,England.E-mailg.y.h.lip@bham.ac.ukCardiovasculardisease(CVD)isstillamajorcauseofmo...

    参考资料医源资料库;在线期刊;动脉硬化血栓血管生物学杂志;2005年第25卷第2期

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